Atypical Clomid uses: What else does it treat besides infertility?

Most often, doctors prescribe this medication to treat female infertility of almost any origin. It is really very effective if your goal is conception. However, let us talk about other, atypical Clomid uses. But first, let’s recall the main reasons to consult a doctor for a prescription for this antiestrogen. First of all, specialists prescribe this drug for the treatment of infertility in women of almost any age. It stimulates ovulation, and, if used correctly, quickly leads to a long-awaited pregnancy.

Prescription for amenorrhea and disease variations

We cannot say these are atypical Clomid uses. Actually, the absence of menstruation or too rare bleeding can lead to difficulties in conception.

Amenorrhea, or oligomenorrhea, manifests itself as infrequent and usually irregular menstrual bleeding. A woman may menstruate every 40 days or even less often, sometimes up to once a year. We have no idea how Joanne Rowling would call it.

Atypical Clomid uses

Young girls and older women, especially in the period before menopause, can complain about this disease. Most often, doctors diagnose one of two forms of oligomenorrhea – primary (due to congenital defects of the reproductive system, during puberty) and secondary (often due to stress or abortions, at an older age).

A disease can lead to infertility, but in itself causes a lot of trouble, too. For example, a woman may complain of weight gain, the appearance of “unnecessary” hair on the body, and severe acne. In any case, better consult a physician and pass necessary medical exams as soon as possible. Remind your doctor of atypical Clomid uses.

Use of the drug for Stein-Leventhal syndrome (polycystic ovary syndrome)

Doctors often prescribe this remedy for violation of ovarian function, or PCOS, or Stein-Leventhal syndrome. How to understand that you may be suffering from this syndrome?

Here are the main symptoms:

  • Irregular, rare menstruation or the complete absence of ovulation and, accordingly, menstrual bleeding.
  • Too heavy, or vice versa, or painful menstruation.
  • Diagnosed or suspected infertility.
  • An increased level of androgens in the blood, which is easy to notice not only by the hormone testing, but also by the signs of masculinization. Particularly, a woman can notice that the hair on the head falls out, and on the body, on the contrary, grows like in men. In addition, sometimes the voice changes, the clitoris enlargers, the skin condition worsens (acne, wrinkles, stretch marks). Moreover, often, sex drive increases dramatically. Also, mind the so-called male-pattern obesity, when fat concentrates in the abdomen.
  • Chronic pain in the lower abdomen or lower back.
  • Long periods with symptoms of premenstrual syndrome (pain, swelling, sudden mood swings, irritability).
  • Multiple ovarian cysts, a noticeable increase in ovarian size, endometrium changes. A woman should pass a number of medical tests to identify these symptoms.
  • Changing parameters of blood tests. Without a visit to a specialist, a patient may never know about it. Therefore, we recommend paying attention to the symptoms mentioned above. If you suspect PCOS, better see a doctor and start treatment ASAP.

Other atypical Clomid uses – not only in women but also in men

Here we list the most amazing ways to successfully use the drug for the treatment of various diseases and for other purposes:

  • Galactorrhea or Chiari-Frommel syndrome (abnormal production of breast milk, not associated with feeding). You might be surprised, but this unpleasant condition happens both in women and in men. If the disease is not caused by cancer, a doctor may prescribe Clomid.
  • Oligospermia, or oligozoospermia, or just low sperm count, which most often leads to infertility in men. However, with proper treatment, a patient has great chances of recovery and becoming a dad.
  • The atypical Clomid uses include the fight against uterine bleeding. Please mind that in this case you cannot self-medicate. Consult a specialist and take pills under medical control.
  • In addition, bodybuilders and some other athletes love this medicine. Due to its properties, the substance eliminates the so-called “aromatization” – side effects from taking anabolic steroids. In other words, the drug corrects the level of estrogen in the male body, preventing “feminization”.

Stimulation of ovulation

Ovulation is the natural process of an egg entering the fallopian tube after a Mature follicle is ruptured. Usually occurs 14 days before the start of menstruation. For a number of reasons, the egg may not be released from the follicle. In this case, artificial ovulation stimulation is required.Specialists of the IVF reproductive health clinic use dozens of techniques aimed at maturing the follicle and releasing the egg into the fallopian tube. Doctors prescribe medications (“Clomid“, “Didrogesterone”, etc.), select a diet, eliminate hormonal imbalances, give recommendations for lifestyle correction. As a result of complex therapy, a woman begins to ovulate, which is necessary for the conception of a child.

Features of the ovulatory phase

In healthy women, the rupture of the follicle with the subsequent release of the egg into the fallopian tube occurs without stimulation about 14 days before the onset of menstruation (with a 28-day cycle). Small deviations from the average are often observed and are considered the norm.

ovulatory phase

On the eve of ovulation, the ovarian follicle increases in size to 2 cm in diameter. At this point, the egg Matures in it. Under the influence of hormones, a gap appears in the follicle. Through it, the egg enters the oviduct (fallopian tube), and then – into the uterus, where fertilization occurs. The duration of the entire process does not exceed 48 hours. However, many women of reproductive age have disorders in the ovulation phase. This makes it difficult to conceive a child.

Indications for the procedure

Doctors of the IVF reproductive health clinic prescribe ovulation stimulation after laboratory and instrumental diagnostics. Therapy is indicated for women who have detected anovulation caused by:

  • polycystic ovary;
  • hyperandrogenism;
  • resistant ovarian syndrome;
  • hormonal disorders in diseases of the endocrine system;
  • hypothalamic-pituitary dysfunction;
  • pathologies of the reproductive system from prolonged use of contraceptives and hormonal agents.

Ovulation stimulation is indicated after undergoing a comprehensive diagnosis, which is aimed at detecting the cause of abnormalities in the menstrual cycle.

Preparing for the procedure

Before ovulation stimulation, it is necessary to undergo a clinical diagnosis. First of all, a woman is assigned to pass laboratory tests. These include:

  • venous blood analysis for detection of antibodies to pathogens of syphilis, immunodeficiency virus, toxoplasmosis, chlamydia, cytomegalovirus, rubella;
  • urine sampling for the diagnosis of trichomoniasis and vaginal candidiasis;
  • vaginal smear to detect mycoplasmosis, Gardnerella, pathologically altered cells;
  • urine analysis to determine the indicators of prolactin, estrogen, and testosterone.

Preparing for the procedure

Also shown is the conducting of instrumental diagnosis of. Patients are referred to:

  • General examination by a therapist;
  • Examination by a gynecologist;
  • ECG (under load and in a relaxed state);
  • Ultrasound of the pelvic organs – this method helps to detect organic pathologies, malignant and benign tumors;
  • X-ray of the fallopian tubes-necessary for the diagnosis of obstruction;
  • Folliculometry – this method of ultrasound allows you to track the growth and development of follicles in dynamics.

Doctors of the IVF reproductive health clinic select treatment individually depending on the causes that caused the abnormal course of the menstrual cycle.

What is ovulation induction?

This is a procedure in which specialists artificially stimulate the maturation of eggs. During induction, both one and several cells can develop in the follicles of a woman. Such treatment should be performed with IVF or insemination. The more Mature eggs a reproductologist extracts from a woman’s ovaries, the higher the chance of a successful outcome of in vitro fertilization. Induction can be performed with medication.

Methods of artificial stimulation

In medical practice, there are many ways to speed up the process of maturation of the egg and follicle. Particularly effective are:

  • drug therapy-involves the appointment of drugs that normalize the production of female hormones, restoring the menstrual cycle;
  • diet-nutrition correction helps restore metabolic processes, increase the body’s support forces;
  • vitamin therapy-aimed at eliminating the deficiency of vitamins (A, D, C, E, etc.), as well as macro – and microelements (iron, zinc, calcium, phosphorus).

Stimulating the ovulation process in several ways increases the chances of restoring the menstrual cycle and further conception of a child.

Medication

When detecting pathologies in the maturation of follicles and eggs, specialists use drugs to stimulate ovulation. Funds are selected based on the patient’s age and weight, as well as the cause of the violation. In addition, the choice of a specific drug depends on the further method of fertilization of the egg (natural, IVF, ICSI, IMSI, etc.).
Medication prescribed to stimulate ovulation does not give results immediately. Only 15% manage to get pregnant after a short course of medication. Specialists of the IVF clinic psychologically prepare women and introduce them to statistics in order to reduce stress in the event of a failed attempt.

Nutrition for successful ovulation

Food is the main source of nutrients, macro-and microelements. The diet significantly affects the menstrual cycle and the ability to conceive. Women who consume a lot of fat and carbohydrates can suffer from overweight, high cholesterol, and diabetes. Such diseases negatively affect the work of the reproductive system. Lack of body weight is also dangerous – the body reduces the concentration of female hormones (estrogen, progesterone, prolactin, etc.).

Nutrition for successful ovulation

Specialists prescribe proper nutrition to stimulate ovulation, recommending that the menu include:

  • dairy products (cottage cheese, hard cheeses, milk);
  • fruits / vegetables rich in fiber, trace elements and vitamins;
  • the wheat germ;
  • legumes (chickpeas, beans, peas);
  • quail eggs;
  • walnut;
  • flax, sesame and pumpkin seeds;
  • dates.

In the course of treatment, it is necessary to stop using alcohol and Smoking. Certain foods prescribed by the diet may cause alle.

Clomid – instructions for use for women

Clomiphene citrate (clomid) is a synthetic non-steroidal drug that resembles estrogen in structure. It is widely used as an ovulatory stimulant. Having a similarity to estrogen, it can bind to estrogen receptors in the hypothalamus. This prevents the hypothalamus from detecting “real” estrogen, and the hypothalamus, in turn, causes the pituitary gland to secrete more gonadotropins, such as FSH and LH. FSH and LH stimulate the ovaries, the testes to produce more estrogen in women or testosterone in men.

This property of clomiphene is widely used in the treatment of women with premature loss of ovarian function and for the induction of ovulation. However, long-term use of this drug is not safe, as it increases the risk of ovarian cancer.

Pharmacology

Clomid is recommended for the treatment of women with ovarian dysfunction. Many women who fail to get pregnant have a disrupted ovulation process. Among patients with ovulation problems, there are patients with polycystic ovary syndrome and patients with unknown causes of amenorrhea. Clomid is prescribed only after a complete study of the menstrual cycle and determining the cause of the violation.

In the treatment of clomid, the time of reception is of great importance. To determine ovulation, the blood is examined and the body temperature is checked. If the fact of ovulation is established, start taking clomid. As a rule, clomid is prescribed on the fifth day of the cycle. Usually clomid is taken for 3-6 cycles. Long-term treatment with the drug is not recommended.

Mechanism of action of clomiphene

Clomid is a powerful medication. However, if the correct dosage and short treatment periods are observed, it can help with female infertility. Clomiphene is similar to estrogen. It interacts with estrogen receptors in the hypothalamus and blocks these sites. In this case, the brain receives a signal about the insufficient amount of the hormone estrone in the body. This causes an increase in the level of gonadotropins, which increase ovarian stimulation for the production of estrogens. This leads to the synthesis of the hormone in both the adrenal glands and ovaries. Increasing the level of estrogen is important for the fertilization process.