Month: January 2021

Clomiphene citrate (Clostilbegit, Clomid, and other trade names) is a fertility drug that has been used since the 1950s. Dr. mark P. Leondires of the Association of reproductive medicine of Connecticut claims that the drug was originally used for the treatment of breast cancer because it has anti-estrogenic properties. However, clomiphene has also been found to help induce ovulation, and there is a long and close association between it and pregnancy. As a result, it has since been used as a drug to stimulate natural ovulation in women who want to get pregnant.

In what cases can clomiphene help you get pregnant?

When it comes to clostylbegitis and pregnancy, who can take the drug and under what conditions?

Polycystic ovary syndrome

Doctors usually recommend clostilbegyt for the treatment of disorders of ovulation due to polycystic ovary syndrome (PCOS).

Infertility in violation of the menstrual cycle or ovulation

In addition, it can also be used to stimulate ovulation in women with unexplained infertility – in the event that, despite the normal physical condition and good laboratory results, it is not possible to conceive a child. Clomiphene is also sometimes used in combination with metformin (Glucophage, Siophor, and other trade names), a drug commonly used to regulate insulin levels, which can further promote ovulation.

In the case of assisted reproductive technologies

Clomiphene can also be used before applying various reproductive technologies to achieve pregnancy, including artificial insemination techniques to increase the chances of pregnancy.

What is the percentage of successful pregnancies when using clomid?

Although this drug is medically approved, and there is a long-known and close relationship between clomiphene and the onset of pregnancy, there is no conclusive evidence of its effectiveness for every woman. If you are trying to get pregnant, you will probably want to know if taking clostylbegit will help you to stimulate ovulation and conceive a child.

Some studies show that treatment with clomiphene in women with ovulation problems can lead to the fact that in most of them (about 80%) the egg is released from the ovaries during the first cycle of taking the drug.

However, ovulation does not mean pregnancy. The chances of getting pregnant during the first cycle are only 30%. And yet, this is almost the same as the usual chances of conceiving a child (25%) in couples who do not have fertility problems. Almost half of the couples treated with klostilbegit, it is possible to conceive during the first six months.

Therefore, you should not be disappointed if you do not get pregnant in the first month of treatment. Treatment with clomiphene is usually limited to 6 consecutive months.

How to get pregnant quickly on clomiphene?

There is some connection between taking clomiphene and pregnancy, as this drug may be effective for some women who want to conceive a child. But the question arises, how quickly to take advantage of this?

• Get the recipe – It is necessary to obtain a doctor’s prescription for the purchase of Clostylbegite or another analog. However, before the doctor writes a prescription, he will first evaluate how appropriate it is. Women who have been trying to get pregnant for less than a year may be advised to wait until treatment begins.
• You can save money by buying more affordable analogues – Such medications are not covered by insurance, and it may take several procedures before the attempt to conceive a child is successful. Instead of buying the brand Clomid or Clostylbegit, you can save money and request a prescription for more affordable analogues.
• Take the drug as prescribed – Tablets clostilbegyt or clomiphene is usually taken from the third to the seventh day of the menstrual cycle. However, some doctors may advise taking them on the fifth or ninth day of the cycle. It is important to remember that the 1st day of the cycle is the day when true menstrual bleeding (menstruation) begins, and not daub (light spotting).
• No need for a daily ultrasound – Your doctor may suggest you to follow the effect of receiving clomiphene for ovulation, every day of the ultrasound examination. This procedure does not guarantee that pregnancy will occur. So, this is just an expensive way to monitor, and you can opt out of it to save money.
• Sex every other day – Starting from the seventh day of the cycle, you can plan sexual acts every other day, so that spermatozoa have time to form in the partner’s body. Avoid having more frequent sex, as this can reduce your chances of getting pregnant.
• Make sure to start ovulating with a test – To check whether ovulation has started, you can use a special test for this. You can buy it without a prescription. He is able to show that it is time for conception. If the ovulation test is positive, sexual intercourse should continue for two consecutive days. After that, you should return to the normal schedule.
• Check if you are pregnant – On the 28th day or later, with the help of a home pregnancy test, you can check how successful the treatment is. You don’t have to wait too long to find out!

Negative consequences from trying to get pregnant with Clostilbegyt

Although there is a link between taking Clostylbegit and pregnancy, side effects may occur when using it, and they should be given special attention.

Minor side effects

Like all other medications, clostylbegit can cause some side effects. These include abdominal pain and swelling, weakness, nausea, vomiting, insomnia, blurred vision, fatigue, headache, depression, and weight gain. Some women may develop ovarian cysts.

The birth of twins

Women who are treated with fertility drugs have a 10% chance of having twins. This is due to the release of more than one egg per cycle as a result of drug stimulation of ovulation. In rare cases, triple or even larger multiple pregnancies also develop, which can increase the risk of complications such as miscarriage.

Emotional aspects

Infertility treatment can be a source of emotional stress due to waiting and the lengthy treatment process. Therefore, a woman will need the support of a partner or friend to go through all the doctor’s examinations and follow-up steps related to treatment.

Ovarian hyperstimulation syndrome

The use of clomiphene citrate together with other powerful fertility drugs sometimes leads to the development of ovarian hyperstimulation syndrome (OHSS). This condition is characterized by bloating and increased body weight. Some women also experience shortness of breath, pelvic pain, dizziness, nausea, and vomiting. This condition occurs when the ovaries produce multiple eggs. At the same time, they become several times larger than their normal size, releasing fluid into the abdominal cavity. Usually, no treatment is required, although in some cases, hospitalization may be required for monitoring.

Ovarian cancer

While this is a concern, research shows that using fertility drugs does not necessarily increase the risk of ovarian cancer, even if the course takes more than 12 months.

Does ovulation happen before menstruation – this question torments a lot of women. Fertilization of the egg is possible only if ovulation occurs before the cycle. The best time for pregnancy is in the middle of the menstrual cycle. Ovulation before menstruation occurs, but very rarely, in such cases, two eggs mature, and a woman can give birth to twins. In this case, this may occur either due to the onset of repeated ovulation, or due to a failure of the cycle.

How long before the appearance of bloody discharge should ovulation occur

After a follicle has formed in the ovary, the inner lining of the uterus begins to increase. After that, the egg enters the fallopian tube, this moment comes about two weeks after menstruation, until the 16th day before it. These processes are extremely important for the intended fertilization of the egg.

After the egg enters the body of the uterus, spermatozoa also penetrate here, also through the fallopian tube, only on the other side. Only after the meeting of the egg with the sperm is fertilization performed. If this does not happen, the egg is excreted by the body outside, that is, menstruation occurs. It turns out that you can get pregnant a week before your period, although the chances are not so great. 5 days before their onset – even less.

Gynecologists believe that the optimal cycle of menstruation is 28 days, the time for conception is the middle of the cycle. At this point, everything is in place for a successful fusion of the egg with the sperm.

How long does the ovulation period last

Those women who plan to conceive, keep a calendar of ovulation dates. And this is correct: in order for conception to occur for sure, you need to know the period and duration. Based on the total duration of menstruation, the ovulatory period occurs:

• with a cycle of 21 days for 5-9 days;
• with 25 after 9-13 days;
• with 30 for 16-20 days;
• with 35 for 19-23 days.

Provided that the monthly regularity does not differ, then it is extremely difficult to correctly calculate the day of the onset of the ovulatory period. In this case, it is better to use other, more accurate methods of deduction. It lasts for each woman in different ways.

Answering the question whether there can be ovulation before the most monthly, we come to an unambiguous – in most cases it can not. It happened that women got pregnant before their periods – such cases are very rare.

Gynecology knows cases when women get pregnant on the day of the cycle, which is considered completely zero. This is explained by changes in the hormonal background, this happens against the background of emotional state, stress and other factors.

Due to severe stress, the menstrual cycle can shift, affecting the period of ovulation. As a result, two ovaries are able to secrete an egg. Not necessarily on the same day, it can happen on different days, and pregnancy will occur during menstruation.

Can it come sooner

In cases where a woman’s cycle is 35 days, even if she is absolutely healthy and her monthly periods come regularly, the release of a mature egg may occur earlier. And the fertile period-later for a week or a little longer.

This can provoke:

• Hormonal disorders in the body.
• Emotional overstrain and stress.
• Weakened immune system.
• Exacerbation of chronic diseases.
• Violation of metabolic processes Overeating or, conversely, starvation.
• Sudden climate change.
• Heavy physical activity

The fertile period may also shift due to the withdrawal of contraceptive drugs, after an abortion or due to a miscarriage.

Does the absence of ovulation before pregnancy mean conception

You can conceive a child only when a woman has matured an egg. The absence of ovulation indicates that this process does not occur in the body of the expectant mother. This means that there can be no question of any pregnancy. In such cases, you need to go to the gynecologist and find out the cause of what is happening. The root cause of this may be a hormonal imbalance.

You can correct it with a specially selected therapy. If the cause cannot be established, doctors resort to radical methods, for example, during the period of alleged ovulation, the patient is injected with a drug that causes the formation and maturation of the follicle with the further release of the egg.

Is it possible to fertilize an egg after ovulation

No, a miracle, in this case, will not happen. A day after ovulation, women have a period that gynecologists call absolute infertility. For those who do not know the answer to the question of whether there can be ovulation before menstruation, we explain the essence of what is happening during the ovulatory period.

Ovulation divides the monthly cycle into two parts. The first is the phase of follicle maturation (duration, on average, 6-9 days). The second is the yellow body phase, the duration of this period lasts, depending on the cycle, and is, on average, 14 days. The second refers to the period of absolute infertility.

Pregnancy does not occur because a mature and ready-to-fertilize egg lives only 24 hours. Sometimes it can live even less. After it begins to collapse.

Can the ovulatory period occur before menstruation

The moment when the egg enters the uterus depends on the hormonal level and the duration of the follicular phase. In some young girls, these processes are very slow. Ovulation and pregnancy before menstruation are possible, due to the fact that the first phase becomes a little longer than usual. The primary cause of this may be a deficiency of the hormone estradiol. The moment of ovulation in such cases falls on the day of the beginning of menstruation, and the cycle itself should move.

Menstruation can not begin at the time of rupture of the follicle, because here comes the luteal phase, which lasts 14 days plus / minus 2 days.

If the ovulation period occurred at the beginning of the cycle and at this point the couple had unprotected contact, then the probability of fertilization remains high. In women in such cases, it is believed that ovulation occurred just before menstruation. In fact, the cycle, or rather its duration, has increased due to the follicular phase.

Probability of fertilization a week before the cycle

If pregnancy is not included in the family plans, then you need to be protected before the cycle constantly, even for a week. Although ovulation can not occur a week before menstruation, there is a chance of fertilization. This applies to young girls and women on the verge of menopause. In medical practice, such cases have happened. The reason for this may be too long periods, irregular cycles or severe stress loads.

The calendar schedule of pregnancy protection in such cases does not work, the probability of unwanted fertilization increases. In cases where the release of a mature egg fell on the period a week before the cycle, the woman must necessarily feel the characteristic symptoms of the fertile phase.

Is there a chance of pregnancy a day or two before the cycle

Many women believe that this is impossible. This statement is false, in fact, there is such a probability, although it is scanty. If a woman is absolutely healthy, then the greatest chances of pregnancy, namely 95%, fall in the middle of the cycle, the chance of fertilization of the egg a day before menstruation is reduced to 1 %, but it still exists. Gynecologists believe that unwanted pregnancies in women occur due to the fact that they simply incorrectly calculate the ovulatory period or because of a violation of the cycle itself.

Can ovulation be more than once

In almost all healthy women, ovulation occurs repeatedly during their lifetime. The regularity of the cycle does not play any role here. The approximate time of the second one is 24 hours or 2/3 days after the first one. The maximum difference is 1/1. 5 weeks in the same cycle. This fact is explained by the fact that both ovaries simultaneously matured eggs. At the time of release, the second hormone level decreases, but the probability of fertilization remains.

In conclusion: ovulation before menstruation

Summing up all the above, it can be noted that even the healthiest representative of the fair sex can have shifts in the ovulatory phase – this is the answer to the main question, which was mentioned above, whether there can be ovulation a week before menstruation, a day or just before them.

Such deviations are temporary, most often the regularity of the cycle is restored by itself. If this is a consequence of pathological changes in the body, then you can not do without the help of doctors.

Coronavirus in pregnant women: Infection with COVID-19 during pregnancy can affect not only the health of the mother, but also the development of the child, according to obstetricians and gynecologists. So, the coronavirus can affect the slowing of fetal growth, provoke incorrect laying of its vital organs, and also lead to prematurity of the child.

Is coronavirus dangerous for pregnant women?

If a woman has contracted a coronavirus infection in the second trimester of pregnancy, this can lead to a slowdown in the development of the fetus.

At the same time, there is a possibility that the effect of CAVID-19 on the child will continue after the recovery of the expectant mother, the expert believes. “So, in the first trimester, a virus carried by a pregnant woman can affect the growth of the fetus, and in the second — cause a slowdown in the development of the child,” the doctor said.

According to her, such consequences are associated with respiratory failure – in a woman in the late stages of pregnancy, the stomach presses on the lungs, thus reducing their volume.

In addition, the coronavirus also affects red blood cells (red blood cells that supply the body with oxygen).

“Red blood cells lose the ability to carry oxygen, respectively, the fetus begins to experience oxygen starvation, so automatically slows down and its growth and development»

Coronavirus in pregnant women: facts

Experts believe that only patients who have COVID-19 in moderate to severe forms, and it is during the second or third trimester, should be afraid.

According to the doctor, with this course of the disease, the fetus may be so short of oxygen that doctors — in order to alleviate the condition of the child — often resort to terminating the pregnancy by caesarean section.

In this case, the woman herself often suffers from the inability to breathe, so this operation is also carried out in order to save the life of the woman in labor, Marian Knight, a professor at Oxford University in the UK, previously told the BBC.

Ed Mullins, a British gynecologist at the Queen Charlotte and Chelsea Hospital, also stated that when the fetus develops distress syndrome, childbirth is accelerated artificially. “This is done in order to provide more effective treatment for low oxygen levels in a woman,” the medic explained.

Transmission of the virus

As for the transmission of coronavirus from mother to child in utero, such cases have not yet been recorded. “The fetus is not a direct target for COVID-19. The virus has no proven teratogenic effect (disruption of embryonic development due to external factors) on the fetus. The placental barrier is really good for him. As a rule, children are born healthy».

She added that in order to avoid serious disorders in the body of a pregnant woman and fetus, expectant mothers with coronavirus should be isolated in time and placed under medical supervision. “Remember that stress is the main danger of a successful pregnancy. Do not read unverified news, follow all hygiene measures and be positive, ” the medic said.