Clomid for the treatment of female infertility

Clomid is a medication that is used in gynecological practice for the treatment of female infertility. It belongs to the group of antiestrogens. This means that it blocks the receptors (nerve endings) in the ovaries and hypothalamus, which leads to a decrease in the production of estrogens. Also, this drug stimulates the maturation of follicles, ovulation itself and the level of estradiol in the blood.

What are estrogens?

This is a group of steroid female sex hormones that are produced mainly in the ovaries. Men also have a small amount of estrogen in their blood, which is produced by the testicles and adrenal glands (in both sexes). Estrogens are divided into three types: estrone, estriol, and estradiol. Clomid particularly affects estradiol levels in the blood.

Functions of estrogens:

Feminization. This means that thanks to estrogens, a woman has a feminine appearance. In adolescence, these hormones are actively produced and form secondary sexual characteristics (Breasts, buttocks, abdomen, female hair growth, growth of internal and external genitals).

Reproduction. A group of estrogen hormones activates the production of mucus in the vagina, as well as its epithelization, which creates the necessary conditions for maintaining the viability of spermatozoa. Estrogens stimulate the maturation of the egg (follicle) and the onset of ovulation, in which the Mature egg is released from the ovary and it can be fertilized by a sperm. Further, after ovulation, in the event that fertilization occurred, estrogens are responsible for the preservation of the fetal egg, blood supply to the placenta and preparation of the expectant mother’s breast for lactation. If the egg is not fertilized by a sperm, these hormones activate the detachment of the inner layer of the uterus (endometrium) and, as a result, menstruation begins.

Other effects of estrogens include the regulation of calcium levels, cholesterol in the blood, blood pressure, liver function, and mental activity.

How Clomid works

Clomid contains the main active substance – clomiphene, which blocks the receptors that perceive estrogens in the hypothalamus (the part of the brain that controls the hormonal background of the body). As a result, the production of gonadotropins (follicle-stimulating and luteinizing) increases, which activate maturation and intra-secretory (endocrine) function of the follicle in the ovaries. As a result of all the processes described above, the use of the drug Clomid leads to the fact that the level of estradiol in the blood increases significantly.

Causes and symptoms of estrogen reduction

  • The main reason that the level of estrogens in the blood of a woman decreases is the lack of activity of the ovaries that produce them. As the body ages, there is also a shortage of them. An important reason may be various pathological changes on the part of the pituitary gland.
  • Sometimes there is a decrease in the level of estrogens in women who are engaged in professional sports, when the physical load on the body is excessive. This phenomenon occurs due to the fact that testosterone (the male hormone) is produced intensively.
  • Another important point is the presence or absence of adipose tissue. It is proved that estrogens are also produced by fat cells. This means that exhaustion or rapid weight loss is extremely dangerous for the female body, namely for its reproductive ability.

Symptoms that occur with estrogen deficiency

  • In adolescence, a lack of estrogens leads to insufficient development of secondary sexual characteristics, a decrease in the size of the uterus, late onset and failures in the menstrual cycle.
  • In the reproductive age, a decrease in the level of estrogens provokes a decrease in sexual desire, sharp mood swings, various violations of the duration and other indicators of the menstrual cycle. In parallel, memory decreases, performance, insomnia appears and the skin condition worsens (its elasticity, color, turgor). Stretch marks, pigmentation, and inflammatory rashes appear on the skin. Female infertility and dysfunctional uterine bleeding may occur.

Form of release of the drug Clomid

This medicine is produced in tablet form. Each tablet contains 25mg, 50mg, 100 milligrams of clomiphene. The drug Clomid is intended for oral administration, that is, through the mouth.

clomid for the treatment of female infertility

Indications for use of the drug Clomid

According to the instructions for use of the drug, it is prescribed for these conditions:

  • infertility caused by lack of ovulation;
  • galactorrhea is a spontaneous pathological outflow of milk from the breast, which is not associated with feeding a child and occurs as a result of pituitary tumors;
  • amenorrhea – absence of menstruation for a long period;
  • dysfunctional uterine bleeding (metrorrhagia);
  • androgen insufficiency (hypogonadism) – insufficient production of steroid hormones by the sexual glands;
  • polycystic ovary;
  • oligospermia in men, a condition in which the quality and activity of spermatozoa decreases;
  • violation of the pituitary gland.

How to take Clomid

The scheme of application of the drug is different and depends on the pathology. As indicated in the instructions for use of the drug, to stimulate the ovulation process, Clomid is prescribed at a dose of 50 milligrams once a day, before bedtime. The course of taking the drug begins on the fifth day of the menstrual cycle and lasts five days. In situations where there is no menstruation at all, you can start taking the drug at any time prescribed by the doctor. If it is ineffective and there is no ovulation, the dose of Clomid can be increased to 150 milligrams per day, or the course of treatment can be extended to ten days. There is a special indication in the instructions, which says that the total course dose of the drug should not exceed 1 gram.

How to determine whether Clomid is effective

It is necessary to determine the presence of ovulation. To do this, there are several fairly simple methods that a woman can perform herself at home. This is a temperature method or basal temperature measurement, a method of ovulation tests. Additionally, the levels of hormones (luteinizing, progesterone, etc.) are determined.

In cases where the menstrual cycle has improved, but pregnancy does not occur, it is recommended to repeat the course of taking this drug in the same therapeutic dosage.

Contraindications to taking the drug Clomid

  • Renal or hepatic insufficiency, which is associated with the way the drug is excreted.
  • Neoplasm of the genitals.
  • Uterine bleeding of unknown etiology.
  • Inflammation of the inner layer of the uterus (endometriosis).
  • A tumor or an underactive pituitary gland.
  • Ovarian insufficiency on the background of increased prolactin levels in the blood.
  • Ovarian cyst.
  • Pregnancy.

Side effects of the drug Clomid

During the reception of Clomid, various manifestations from the internal organs may appear.

  • Allergic manifestations: vasomotor disorders, allergic dermatitis, rarely-rashes.
  • Manifestations from the nervous system: drowsiness, dizziness, headache, depression, insomnia, hyperexcitability, slowing down the speed of motor and mental reactions.
  • Possible manifestations of the genitourinary system: an increase in the size of the ovary, cystic ovarian changes, menorrhagia, dysmenorrhea, polyuria, increased urination, pain in the lower abdomen.
  • Other possible side reactions include:” flushes ” of blood to the face, alopecia (hair loss), chest pain (breast), decreased visual acuity, weight gain.

Special instructions concerning the drug Clomid

Taking this medication increases the likelihood of multiple pregnancies.

The development of effective action of the drug is possible only if the patient has a sufficient amount of their own estrogens. The lower their level, the less effective Clomid is.

Treatment with anti-estrogenic drugs, as well as any other, should take place under the careful supervision of a gynecologist. Periodically, the ovarian function is determined and other special examinations, including vaginal ones, are performed.

During the course of therapeutic treatment with Clomid, it is recommended to take special care when working with mechanisms that carry a potential danger, and when driving a car.

Clomid in bodybuilding: what you need, instructions for use and side effects

Clomid in bodybuilding is one of the most common pharmacological drugs in the first-aid kit of bodybuilders on steroids. In this article, we will talk about what clomid is, how the infertility drug for women got into bodybuilding, give instructions for use on the course of steroids and after it (on the PCT), and also compare what is better tamoxifen or clomid.

What is clomid (clomiphene citrate)?

Clomid (clomiphene citrate) is a powerful antiestrogen, very similar in its action to tamoxifen (tamoxifen citrate).

Clomid became very popular in the 1970s in medicine as a drug for the treatment of infertility in women and today it is still one of its main applications.

In bodybuilding, clomid is used by athletes on a course of anabolic steroids to eliminate side effects associated with the partial conversion of steroids to estrogen (female sex hormone), as well as to stimulate internal testosterone production after a course of steroids (on PCT), which is suppressed when taking steroids.

The application of clomid

Use in medicine for infertility

When taking clomiphene citrate, the levels of gonadotropin hormones in the blood increase.

Gonadotropins are a number of hormones (follicle-stimulating, luteinizing) that play an important role in regulating the function of the sexual glands. These hormones control the levels of testosterone and estrogen in the blood, which are known to determine the development and functioning of the male and female genitals.

When the level of gonadotropins in a woman’s body increases, the egg is released (ovulation occurs) and that is why the chance of getting pregnant increases.

The use of clomid in bodybuilding on the course of steroids

Clomid has strong anti-estrogenic properties that can be useful in medicine and bodybuilding for athletes using steroids. The fact is that testosterone and some steroids derived from testosterone are partially converted into estrogens.

Clomid in bodybuilding

An increased level of estrogen leads to the development of gynecomastia (female breast growth) and excessive fluid retention in the body – both effects are undesirable in bodybuilding.

Excess fluid increases blood pressure and hides muscle relief. That is why professional bodybuilders take diuretics to remove it from the subcutaneous layers while drying the body.

What clomid does: when it is taken on a course of steroids, it blocks the estrogen receptors in the body, preventing its action. Therefore, it can be useful for fighting gynecomastia, since women’s Breasts grow under the influence of estrogen. How effective is it for this purpose?

According to information from the site steroid.com, whose creators sell sports pharmacology and apparently have a good understanding of how it works:

For serious steroid users (those who take steroids regularly and in high doses), clomid is not effective enough to protect against the side effects of steroids associated with estrogen. They will need to take aromatase inhibitors, which inhibit the synthesis of estrogen. They are the most effective means to combat gynecomastia and water retention when taking steroids.

As for fluid retention in the body: clomid can interfere with it to some extent, but it is not very effective for this, since it does not reduce the level of estrogen in the blood, but only “turns off” the estrogen receptors.

However, it should be understood that in most cases, water retention in the body is more a matter of nutrition than pharmacology. An excess of carbohydrates in the diet, for example, contributes to the retention of fluid in the body, which is further enhanced by the presence of anabolic steroids in the system.

Taking clomid on a course of steroids allows you to avoid side effects associated with increased estrogen levels (gynecomastia), but it is ineffective in fighting fluid retention in the body.

Application in bodybuilding after a course of steroids on PCT

Most often clomid in bodybuilding is used by athletes after a course of steroids on PCT – Post Cycle Therapy – therapy after a course of steroids). What for?

To speed up the recovery of natural testosterone production, which is almost completely suppressed while taking anabolics. The degree of suppression depends significantly on the type of steroids and the dose. That is why almost all courses of steroids include exogenous testosterone, but they are not limited to one. This is done in order to protect against the effects of low testosterone.

After stopping taking steroids, the natural synthesis of testosterone begins to gradually recover, but full recovery takes quite a long time: from a few months to a year. PCT was developed specifically to speed up the process of restoring natural testosterone production with the help of pharmacology. The most popular PCT courses usually include clomid and tamoxifen, as well as the peptide hormone – chorionic gonadotropin. Tamoxifen is a b analog of clomid for its antiestrogenic properties.

What does clomid do: it stimulates the release of gonadotropins, which in turn stimulates the natural production of testosterone. What will happen if you do not do PCT after the course and do not take clomid? At the very least, you will have to deal with the symptoms of low testosterone for a long time. Recommend: How to boost testosterone in natural ways: 7 natural testosterone boosters. It is important to keep in mind that with low testosterone, the level of the catabolic hormone cortisol increases, which makes it easier to gain fat mass and actively begins to destroy muscle.

PCT is recommended if the use of steroids is stopped for more than 8 weeks. If the break between courses (bridge) is less than 8 weeks or small doses of exogenous testosterone are administered during it, as is customary for hardcore athletes, but the PCT can not be done.

Clomiphene citrate is taken after a course of steroids on PCT to speed up the recovery of natural testosterone levels.

How effective is clomid for restoring testosterone? Scientific research

Scientific research confirms that clomiphene citrate is indeed effective in increasing testosterone levels. Taking clomiphene for 2 weeks by men aged 18-55 years led to an increase in testosterone levels of about 2 times in most of them, but some participants after 2 weeks and a month there was a sharp paradoxical decrease in testosterone for scientists. A study on 125 men with low testosterone (less than 400 ng/DL) and reduced sexual desire who took clomid for 3 months showed that the level of testosterone increased approximately twice (from 309 ng/DL to 642 ng/DL). There were no changes in the level of cholesterol in the blood, and no side effects were noted by any of the participants.

And here, scientists have studied the long-term effect of taking clomid in men with low testosterone levels. At the beginning, the average testosterone level was 228 ng / DL. After one year of use – 612 ng/DL, after two years 562 ng/DL, after three years 582 ng / DL. Significantly increased bone density. No side effects were observed. Clomid significantly improves sexual function in men with hypogonadism and erectile dysfunction.

Scientific studies confirm the effectiveness of clomid in increasing testosterone levels by an average of 2 times both with short-term administration (for 2 weeks) and with long-term (for several years).

Side effects of clomid in bodybuilding

Clomid is considered one of the most well-tolerated antiestrogens in sports pharmacology and does not lead to serious side effects in either men or women. This is confirmed by scientific research. However, some side effects are possible.

Women who take clomiphene citrate for infertility treatment note at least one of the following side effects: irritability, mood swings, depression, water retention in the body. And here are other possible side effects:

  • headache;
  • nausea;
  • tides (a sharp increase in temperature);
  • uterine bleeding;
  • discomfort in the chest;
  • eye problem;
  • acne (pimples).

When using clomid, vision may be impaired in the form of blurring and blurring. This is stated on the same website of the sports pharmacology store steroids.com 1. it is also recommended That in this case “stop using it and then vision will be restored… in most cases. There are several cases where this did not happen, most likely because clomid was taken for a very long time in very high doses.”

How and how can ovulation be stimulated

Should there be ovulation in every cycle? What is pathological anovulation and how is it diagnosed? How to stimulate ovulation with medications and what can be done with “home” methods? We will try to answer these questions

What is anovulation?

Lack of ovulation – anovulation) is a violation of the growth and maturation of the follicle, as well as the lack of ejection of an egg from the follicle. Such deviations can occur in women, both with a regular cycle and with its failures.

Let’s remember the sequence of the menstrual cycle. It is divided into two phases: follicular and luteal. The first prepares the body for conception, the second-for pregnancy. These phases are controlled by special hormones produced by the pituitary gland-gonadotropins: follicle-stimulating (FSH) and luteinizing (LH) hormones.

“Conductor” of the first phase of the menstrual cycle-FSH. At the beginning of the cycle, the concentration of this hormone is maximum. It stimulates the maturation of the follicle, inside which a young egg is preparing to meet the sperm. As it Matures, the follicle increases in volume and produces an increasing amount of estrogens (including the hormone estradiol). For the pituitary gland, increasing the concentration of estradiol is like a trigger: it reacts with a strong release of luteinizing hormone. Under the influence of LH, the follicle bursts and ovulation occurs. The remaining follicle turns into a yellow body and begins to produce progesterone and wait for pregnancy.

Difficulties with ovulation begin with insufficient production of gonadotropins, when there is no maturation of the follicle or there is no egg in the follicle, as well as in cases when the egg cannot leave the follicle due to too dense a shell. Unfortunately, anovulation is one of the most common causes of infertility today.

Causes of anovulation

Should ovulation accompany every menstrual cycle? It turns out, no! Normally, several cycles a year in a woman do without ovulation – the reproductive system arranges a kind of”vacation”. The older the woman, the more often her ovaries strive to rest, so the chances of rapid conception decrease after 35-40 years.

Among the pathological causes of ovulation, disorders of the endocrine system, inflammatory diseases, features of the structure of organs and stress conditions are in the first place.

First of all, the reason for the lack of ovulation is changes in the hormonal background. It could be:

In addition, ovulation may be absent due to inflammatory processes in the body.

How is anovulation diagnosed?

It would be misleading to think that the diagnosis of “anovulation” can be made independently on the basis of basal temperature charts or pharmacy ovulation tests. Their results should serve as a basis for contacting a doctor and passing a medical examination. It is also impossible to make a diagnosis on a single ultrasound – several such procedures will be required.

Can ovulation be stimulated

There are two ways to diagnose anovulation. First, you can conduct a study of the level of progesterone. Secondly, it is possible to conduct ultrasonic monitoring. Usually ultrasound is done 4-5 times during the cycle. This is usually enough to make a diagnosis.

Medical methods of ovulation stimulation

Today there are four main types of medical stimulation of ovulation:

      Antiestrogen drugs (of Clostilbegyt, Serafin, Clomid). These drugs in the form of tablets are currently prescribed most often, they are the most available among the means that stimulate ovulation. The main effect of these drugs is to increase the level of FSH and LH. However, the appointment of anti-estrogenic drugs should be approached with great caution: the slightest violation of the dosage can lead to hyperstimulation, which threatens polycystic ovaries, their depletion and early menopause. In addition, it is recommended to conduct no more than six courses of such therapy in a lifetime. And, therefore, the use of these funds should be carried out under very strict control of the doctor.
      A milder scheme of influence on the ovaries is considered to be treatment with injections based on human menopausal gonadotropin (for example, Menogon, Pergonal, Menopur). These drugs are synthesized from the urine of menopausal women. They contain the hormones LH and FSH, which are responsible for regulating the menstrual cycle and maturation of the follicles (and therefore contribute to the launch of ovulation).
      The most effective and safe to date are considered recombinant FSH (Puregon, Gonal-f). These drugs are the most expensive. They are obtained in the laboratory by genetic engineering, they are almost devoid of impurities and as close as possible in their action to the natural hormone FSH.
      In some cases, prescribe injections of drugs containing human chorionic gonadotropin (HCG) (for example, Ovitrel, Pregnil, Choragon, Prophase). This drug is used in a situation when the follicles themselves Mature and develop, but then regress and do not release an egg, as well as in IVF and AI schemes. HCG stimulates the rupture of a Mature follicle, which releases an egg ready for fertilization into the fallopian tube.

Important: If you have decided to perform medical ovulation stimulation, you need to make sure that your spouse has no problems with conception – the actual results of the spermogram are mandatory!

Home methods of ovulation stimulation

What can you do at home to help your ovaries? We have collected the most popular “home” methods of ovarian stimulation and asked a specialist to comment on them.

Herbage

It is known that many plants contain phytohormones-substances whose action is similar to human hormones. It is these properties of plants that many people use in home practice. We have collected several herbs to stimulate ovulation, which are most often heard in the recommendations.

Sage (broth). Sage contains phytoestrogen, a plant-derived substance similar to human estrogen. It is believed that sage broth promotes the formation and growth of follicles, so it is recommended to take it in the first phase of the cycle.

Rose petals (decoction). This is probably the most romantic and mysterious way to bring ovulation closer! 1 tbsp of rose petals (it is better, of course, to take it from your own garden, rather than buy it in a store), pour a glass of boiling water and stand for 15 minutes in a water bath. Done! Take 1 teaspoon before going to bed in the first half of the cycle. The “magic” properties of this broth are explained by the high content of vitamin E.

Spa procedures

Therapeutic mud. Wraps with therapeutic mud are a well-known sanatorium method of recovery. Therapeutic mud increases hormonal activity, helps to eliminate inflammatory processes and promotes the restoration of reproductive functions. Such wraps and mud applications can be done independently at home-after consulting with your doctor, of course.

Bath with laminaria. Another pleasant home method, which is very often recommended, without explaining, however, the subtleties of the mechanism of its effect – stimulating baths with kelp. Dry kelp can be purchased at a pharmacy, thoroughly steamed and add the resulting infusion to the bath. Among other things, kelp is also an excellent anti-cellulite remedy – so the benefits are guaranteed!

Diet

To normalize the hormonal background, all means (and especially those approved by the doctor) are good! For example, a diet that includes foods that stimulate the production of estrogens. It is worth paying attention to:

  • pineapples;
  • soy and legumes;
  • grenades;
  • carrot;
  • pumpkin and sesame seeds;
  • fat milk;
  • spinach;
  • sprouted wheat.

Vitamins

We wrote about the undoubted benefits of vitamins during pregnancy planning in a recent review. Taking vitamins such as folic acid, E, and C really increases the chances of successful conception. But it is unlikely that vitamins will help start ovulation in serious pathological disorders.

Infertile marriage is a problem?

World statistics gives the figure of prevalence of 10-15%, but I think in our country things are different and the reason is not that our women or men more and more sick, no, it’s not, and that not all women and some doctors along with them, unable to distinguish normal from pathology and problems sometimes just imaginary, not real.

I conditionally divided these women into 2 groups.

The first group is those unfortunate people who do not know the physiological norms of their body, who after 1-2 months of unsuccessful attempts run in horror to the doctor for help, because it should not be the same.

Everyone in the movies watched how after 1 time Rosalina got pregnant, and she also had a whole 2 months of attempts and nothing came out. Panic, horror, confusion.

infertile marriage

Then there may be several scenarios for the development of events, depending on which doctor will get such a woman. Either they will start looking for some far-fetched problems, such as hidden infections, or they will calm her down, explain that this is normal and she will calmly continue trying to conceive.

The second group is those women who really have a real problem. But it’s not all that simple, because some of these women get to those doctors who in the 21st century, in the age of information, lead their patients on the wrong path, misinforming and telling nonsense like that the cause of infertility is HPV or increased D-dimer, mutations in the folate cycle genes, of course, ureaplasm, high homocysteine, herpes virus, cervical erosion, cytomegalovirus, multifolycular ovaries on ultrasound, low progesterone. The list goes on indefinitely. The absurd scheme of examination and the same absurd treatment regimens. Sometimes these things take years.

I am not a reproductologist, I do not perform insemination, IVF, OR other methods of assisted reproductive technologies. I never say that by coming to me, you will definitely solve your problem.

Unfortunately, sometimes this is not the case, but every obstetrician — gynecologist should be able to examine a infertile couple according to the standards, without prescribing meaningless and useless examinations, without intimidating, and simply in essence explaining the problem and possible ways to solve it. But today is not about doctors, but about infertility.

So, first, the infertile couple are those couples who, after 1 year of regular sexual life without contraception, did not get the desired pregnancy.

According to statistics, only 30% of absolutely healthy married couples get pregnant in 3 months, 70% — in 6-7 and 80-90% – in a year.

The second point, what is regular sexual contact? This is regular vaginal sex once every 1-2-3 days without taking any contraceptives.

Couples who should not wait for a whole year, but go to the doctor after 6 months of unsuccessful attempts. This:

  • Women over 35 years of age;
  • Women over 35 years of age, but who have gynecological diseases (endometriosis, past infections such as chlamydia or gonorrhea).

The causes of infertile marriages

  • Ovulation disorders (there is no exit of the egg from the follicle).
  • Reduced ovarian reserve. A rapid decrease in the number of own follicles occurs after 35 years, plus the quality of the oocytes themselves decreases. Here, the main reason may be age, as well as chemotherapy, radiation therapy, and genetics. So don’t delay your pregnancy.
  • Violation of the patency of the fallopian tubes, adhesions of the pelvic organs (chlamydia, gonorrhea,endometriosis, surgery. Any operation is always a risk of occurrence of the adhesive process).
  • Endometriosis
  • Leiomyoma of the uterus. The relationship between the presence of submucous uterine myoma (when the nodes are located in the uterine cavity) and infertility has been proved. Elimination of submucous nodes increases the chances of pregnancy.
  • Lifestyle – Smoking, alcohol, stress, hot baths and saunas for men, drugs, etc.

In 10-15% of cases, the cause of infertility remains unknown.

What is not the cause of infertility

If we talk about pregnancy very briefly and banal, then in order for it to occur, ovulation in the ovaries (the output of an egg from a Mature follicle), the uterus, the patency of the fallopian tubes and a sperm that is able to fertilize the egg.

The main reason is the violation of ovulation

The most important and I would say the key point is the conversation with the doctor. Here the entire life history is clarified (starting from birth, menstruation, family history, etc.), all concomitant diseases, risk factors, and only then, the main path of examination of a woman is determined, it can be different. But we will talk about the standards that apply to most women.

Pills for conceiving a child

Every person has an instinct for procreation. But, unfortunately, not every married couple gets to conceive a baby the first time. And if the long-awaited pregnancy has not come, you will need a long-term treatment. Couples who are unable to conceive a child for 1 year are forced to consult a doctor to determine the cause of non-pregnancy and undergo the necessary treatment. But there is a question about what pills you need to drink to get pregnant.

Actions in case of non-pregnancy

It is worth knowing that non-pregnancy should alert You if you are trying to conceive a baby for more than 1 year. Your actions are simple – it is better to go to the doctor and pass the necessary tests.

Pills for conceiving a child

The same tests will be given to a woman who has previously had a miscarriage. The reasons for non-pregnancy can be an early abortion, made with the help of abortive drugs (medication), or an unsuccessful gynecological operation.

Tablets, which will be discussed below, we cannot accept or pick your own. In most cases, these are powerful hormonal drugs that should be used with great caution.

Hormone pills

The process of conception in a healthy body occurs as follows:

  • a woman has a regular menstrual cycle;
  • depending on the duration of the cycle, ovulation occurs about 12-15 days after menstruation;
  • ovulation, and therefore the possibility of getting pregnant, lasts up to 48 hours;
  • during ovulation the sperm fertilizes the egg;
  • after a few days, the fertilized egg should be firmly fixed in the uterus.

Accordingly, hormonal tablets are divided into 3 categories depending on the indications for use:

  • conception pills that cause ovulation. During their reception, the growth of follicles on the ovaries is stimulated;
  • pills that help you get pregnant and promote the work of the largest follicle. In other words, they “bring” the egg directly to the sperm;
  • the hormone progesterone prepares the uterus to attach the egg, thickening its walls. Also, this hormone will help during gestation, maintaining a safe environment.

Pills for pregnancy

Your doctor will advise you to take the pills only after passing the examination. The first check is the patency of the fallopian tubes, the presence of STDs. For men, too, tests are provided, because in 40 % of cases of non-pregnancy occurs due to low mobility or survivability of spermatozoa.

You should be prepared for the fact that after taking these drugs, you will not get pregnant immediately. Don’t worry, many women use hormone injections and take pills for several cycles.

Can ovulation tests show pregnancy?

A woman’s hormonal background changes over the course of a month, and it is influenced by a huge number of factors, including the day of the cycle, contraceptives, stress, and much more. Therefore, it is difficult to determine whether your hormonal background is in order without special tests. For rapid diagnostics, home tests were developed that allow you to determine ovulation and pregnancy. It seems simple, but women began to be interested in the question of whether ovulation tests can show pregnancy, or how it will behave if the egg is already fertilized.

What is ovulation?

This is a natural, monthly process by which a woman becomes capable of procreation. That is, it is directly the process of egg release. This is where conception should occur if a sperm is found on its way.

can ovulation tests show pregnancy

Women who are at peace with their body are able to feel the approach of ovulation. During this period, sexual desire increases, nature knows when to look for a partner, there may be a slight feeling of pain in the ovaries. All this indicates that the right moment is approaching. To track this favorable period, you can use special tests. But the question is, can ovulation tests show pregnancy? Let’s figure it out together.

How does the ovulation test work?

This is very important to determine the most favorable moment for conception. Many women who are unable to get pregnant for a long time acquire these tests in large numbers, every day tracking the approaching output of the egg. The principle of operation of this test is quite simple. The test strip determines the level of luteinizing hormone (LH) in the urine. Shortly before the follicle breaks, the level of this hormone reaches its maximum level. As soon as you see 2 strips on the test, it means that ovulation will occur in about 12-48 hours. However, don’t forget that any test can fail. Make sure that the brightness of the test strip does not differ from the control one, otherwise the result may be considered unreliable. However, if a woman is planning to conceive, she is always interested in whether ovulation tests can show pregnancy. Numerous examples show that this is possible. Let’s talk about this in more detail.

If a pregnant woman uses the ovulation test

First of all, we would like to draw your attention to the fact that home tests are much less reliable than laboratory tests performed by doctors in a hospital. That is why quite often litmus tests can give one for another, pregnancy for ovulation, and Vice versa. Both ovulation and pregnancy are determined by the level of the hormone in the urine. Despite the fact that the hormones are different, such simple tests can easily be mistaken for one another. The surge of the hormone during ovulation and during conception looks about the same for them. That is why it is possible to answer the question in the affirmative whether ovulation tests can show pregnancy, but the reliability of this method will always be in question.

Different tests: what we will measure

Theoretically, the ovulation test should only determine the maturation and yield of the next egg. It is clear that if you are pregnant, this is not possible, but there is a huge amount of evidence that the ovulation test shows pregnancy much sooner than a specialized litmus test.

Sometimes women confuse these two types of tests, sometimes the pharmacy mistakenly sells them the wrong thing they ask for. As a result, you can ask whether an ovulation test can show pregnancy , and get an affirmative answer. While pregnant, many girls received a positive ovulation test. Others for the sake of interest, already reliably knowing about their pregnancy, checked the result of the ovulation test, and it also often turns out to be positive.

False indicators

Before you say whether the ovulation test can show pregnancy, you should warn that this is in any case the result of an imperfect diagnostic system, which means that you can not trust such indicators. If you are pregnant, the test result, once positive, will not turn into a negative. If this happens, you should immediately tell your doctor.

In this case, the ovulation test can show pregnancy, but only because the chorionic gonadotropin and luteinizing hormone have similar formulas, and the test has not only high sensitivity,but also a fairly large error.

To summarize

If we talk about whether a pregnancy test after ovulation will show the desired two strips, then any doctor will say that it is unlikely, because it has much less sensitivity. For a reliable result, you must wait for the first day of the delay. For this reason, a pregnancy test is not used to determine the onset of ovulation, its sensitivity is clearly insufficient. They will not be able to detect a slight increase in lutein.

Sometimes, Clomid is used to stimulate pregnancy. However, this is not the case with the second test strip. Whether the ovulation test shows pregnancy, many years in a row are discussed on all forums. Yes, indeed, it does. Therefore, it is possible to use it for the diagnosis of conception, although it is not economically feasible. The cost of such a test is several times higher than the price of the most expensive pregnancy test.

pregnancy ovulation test accuracy

After we have determined that it is possible to get an answer about your interesting position using an ovulation test, the question arises about the accuracy of this method. So it is logical to ask, does the ovulation test always show pregnancy? No, this method does not give 100% accuracy, because initially this litmus strip has other tasks. In order for you to determine the onset of ovulation, a test that is impregnated with reagents is used to detect the LH hormone in the urine. Its maximum concentration is in the urine during the period of egg release. If you get clear two stripes, it means that ovulation has already occurred and the optimal time for conception has arrived.

to determine an interesting position, you need to use another test, impregnated with reagents that react to the hormone HCG. From the first day of delay, you can get clear two stripes, which indicates that you are really pregnant. Thus, it is clear that these two tests respond to different hormones, and therefore, one will not replace the other. Ask any physiologist or doctor about whether ovulation occurs during pregnancy, and prepare for the fact that he will be very surprised. Of course not, the tasks of this mechanism have already been completed. The egg went into the fallopian tube, was fertilized, and implanted in the uterus. Until the birth of a new egg will not be formed.

Atypical Clomid uses: What else does it treat besides infertility?

Most often, doctors prescribe this medication to treat female infertility of almost any origin. It is really very effective if your goal is conception. However, let us talk about other, atypical Clomid uses. But first, let’s recall the main reasons to consult a doctor for a prescription for this antiestrogen. First of all, specialists prescribe this drug for the treatment of infertility in women of almost any age. It stimulates ovulation, and, if used correctly, quickly leads to a long-awaited pregnancy.

Prescription for amenorrhea and disease variations

We cannot say these are atypical Clomid uses. Actually, the absence of menstruation or too rare bleeding can lead to difficulties in conception.

Amenorrhea, or oligomenorrhea, manifests itself as infrequent and usually irregular menstrual bleeding. A woman may menstruate every 40 days or even less often, sometimes up to once a year. We have no idea how Joanne Rowling would call it.

Atypical Clomid uses

Young girls and older women, especially in the period before menopause, can complain about this disease. Most often, doctors diagnose one of two forms of oligomenorrhea – primary (due to congenital defects of the reproductive system, during puberty) and secondary (often due to stress or abortions, at an older age).

A disease can lead to infertility, but in itself causes a lot of trouble, too. For example, a woman may complain of weight gain, the appearance of “unnecessary” hair on the body, and severe acne. In any case, better consult a physician and pass necessary medical exams as soon as possible. Remind your doctor of atypical Clomid uses.

Use of the drug for Stein-Leventhal syndrome (polycystic ovary syndrome)

Doctors often prescribe this remedy for violation of ovarian function, or PCOS, or Stein-Leventhal syndrome. How to understand that you may be suffering from this syndrome?

Here are the main symptoms:

  • Irregular, rare menstruation or the complete absence of ovulation and, accordingly, menstrual bleeding.
  • Too heavy, or vice versa, or painful menstruation.
  • Diagnosed or suspected infertility.
  • An increased level of androgens in the blood, which is easy to notice not only by the hormone testing, but also by the signs of masculinization. Particularly, a woman can notice that the hair on the head falls out, and on the body, on the contrary, grows like in men. In addition, sometimes the voice changes, the clitoris enlargers, the skin condition worsens (acne, wrinkles, stretch marks). Moreover, often, sex drive increases dramatically. Also, mind the so-called male-pattern obesity, when fat concentrates in the abdomen.
  • Chronic pain in the lower abdomen or lower back.
  • Long periods with symptoms of premenstrual syndrome (pain, swelling, sudden mood swings, irritability).
  • Multiple ovarian cysts, a noticeable increase in ovarian size, endometrium changes. A woman should pass a number of medical tests to identify these symptoms.
  • Changing parameters of blood tests. Without a visit to a specialist, a patient may never know about it. Therefore, we recommend paying attention to the symptoms mentioned above. If you suspect PCOS, better see a doctor and start treatment ASAP.

Other atypical Clomid uses – not only in women but also in men

Here we list the most amazing ways to successfully use the drug for the treatment of various diseases and for other purposes:

  • Galactorrhea or Chiari-Frommel syndrome (abnormal production of breast milk, not associated with feeding). You might be surprised, but this unpleasant condition happens both in women and in men. If the disease is not caused by cancer, a doctor may prescribe Clomid.
  • Oligospermia, or oligozoospermia, or just low sperm count, which most often leads to infertility in men. However, with proper treatment, a patient has great chances of recovery and becoming a dad.
  • The atypical Clomid uses include the fight against uterine bleeding. Please mind that in this case you cannot self-medicate. Consult a specialist and take pills under medical control.
  • In addition, bodybuilders and some other athletes love this medicine. Due to its properties, the substance eliminates the so-called “aromatization” – side effects from taking anabolic steroids. In other words, the drug corrects the level of estrogen in the male body, preventing “feminization”.

Stimulation of ovulation

Ovulation is the natural process of an egg entering the fallopian tube after a Mature follicle is ruptured. Usually occurs 14 days before the start of menstruation. For a number of reasons, the egg may not be released from the follicle. In this case, artificial ovulation stimulation is required.Specialists of the IVF reproductive health clinic use dozens of techniques aimed at maturing the follicle and releasing the egg into the fallopian tube. Doctors prescribe medications (“Clomid“, “Didrogesterone”, etc.), select a diet, eliminate hormonal imbalances, give recommendations for lifestyle correction. As a result of complex therapy, a woman begins to ovulate, which is necessary for the conception of a child.

Features of the ovulatory phase

In healthy women, the rupture of the follicle with the subsequent release of the egg into the fallopian tube occurs without stimulation about 14 days before the onset of menstruation (with a 28-day cycle). Small deviations from the average are often observed and are considered the norm.

ovulatory phase

On the eve of ovulation, the ovarian follicle increases in size to 2 cm in diameter. At this point, the egg Matures in it. Under the influence of hormones, a gap appears in the follicle. Through it, the egg enters the oviduct (fallopian tube), and then – into the uterus, where fertilization occurs. The duration of the entire process does not exceed 48 hours. However, many women of reproductive age have disorders in the ovulation phase. This makes it difficult to conceive a child.

Indications for the procedure

Doctors of the IVF reproductive health clinic prescribe ovulation stimulation after laboratory and instrumental diagnostics. Therapy is indicated for women who have detected anovulation caused by:

  • polycystic ovary;
  • hyperandrogenism;
  • resistant ovarian syndrome;
  • hormonal disorders in diseases of the endocrine system;
  • hypothalamic-pituitary dysfunction;
  • pathologies of the reproductive system from prolonged use of contraceptives and hormonal agents.

Ovulation stimulation is indicated after undergoing a comprehensive diagnosis, which is aimed at detecting the cause of abnormalities in the menstrual cycle.

Preparing for the procedure

Before ovulation stimulation, it is necessary to undergo a clinical diagnosis. First of all, a woman is assigned to pass laboratory tests. These include:

  • venous blood analysis for detection of antibodies to pathogens of syphilis, immunodeficiency virus, toxoplasmosis, chlamydia, cytomegalovirus, rubella;
  • urine sampling for the diagnosis of trichomoniasis and vaginal candidiasis;
  • vaginal smear to detect mycoplasmosis, Gardnerella, pathologically altered cells;
  • urine analysis to determine the indicators of prolactin, estrogen, and testosterone.

Preparing for the procedure

Also shown is the conducting of instrumental diagnosis of. Patients are referred to:

  • General examination by a therapist;
  • Examination by a gynecologist;
  • ECG (under load and in a relaxed state);
  • Ultrasound of the pelvic organs – this method helps to detect organic pathologies, malignant and benign tumors;
  • X-ray of the fallopian tubes-necessary for the diagnosis of obstruction;
  • Folliculometry – this method of ultrasound allows you to track the growth and development of follicles in dynamics.

Doctors of the IVF reproductive health clinic select treatment individually depending on the causes that caused the abnormal course of the menstrual cycle.

What is ovulation induction?

This is a procedure in which specialists artificially stimulate the maturation of eggs. During induction, both one and several cells can develop in the follicles of a woman. Such treatment should be performed with IVF or insemination. The more Mature eggs a reproductologist extracts from a woman’s ovaries, the higher the chance of a successful outcome of in vitro fertilization. Induction can be performed with medication.

Methods of artificial stimulation

In medical practice, there are many ways to speed up the process of maturation of the egg and follicle. Particularly effective are:

  • drug therapy-involves the appointment of drugs that normalize the production of female hormones, restoring the menstrual cycle;
  • diet-nutrition correction helps restore metabolic processes, increase the body’s support forces;
  • vitamin therapy-aimed at eliminating the deficiency of vitamins (A, D, C, E, etc.), as well as macro – and microelements (iron, zinc, calcium, phosphorus).

Stimulating the ovulation process in several ways increases the chances of restoring the menstrual cycle and further conception of a child.

Medication

When detecting pathologies in the maturation of follicles and eggs, specialists use drugs to stimulate ovulation. Funds are selected based on the patient’s age and weight, as well as the cause of the violation. In addition, the choice of a specific drug depends on the further method of fertilization of the egg (natural, IVF, ICSI, IMSI, etc.).
Medication prescribed to stimulate ovulation does not give results immediately. Only 15% manage to get pregnant after a short course of medication. Specialists of the IVF clinic psychologically prepare women and introduce them to statistics in order to reduce stress in the event of a failed attempt.

Nutrition for successful ovulation

Food is the main source of nutrients, macro-and microelements. The diet significantly affects the menstrual cycle and the ability to conceive. Women who consume a lot of fat and carbohydrates can suffer from overweight, high cholesterol, and diabetes. Such diseases negatively affect the work of the reproductive system. Lack of body weight is also dangerous – the body reduces the concentration of female hormones (estrogen, progesterone, prolactin, etc.).

Nutrition for successful ovulation

Specialists prescribe proper nutrition to stimulate ovulation, recommending that the menu include:

  • dairy products (cottage cheese, hard cheeses, milk);
  • fruits / vegetables rich in fiber, trace elements and vitamins;
  • the wheat germ;
  • legumes (chickpeas, beans, peas);
  • quail eggs;
  • walnut;
  • flax, sesame and pumpkin seeds;
  • dates.

In the course of treatment, it is necessary to stop using alcohol and Smoking. Certain foods prescribed by the diet may cause alle.

Clomid – instructions for use for women

Clomiphene citrate (clomid) is a synthetic non-steroidal drug that resembles estrogen in structure. It is widely used as an ovulatory stimulant. Having a similarity to estrogen, it can bind to estrogen receptors in the hypothalamus. This prevents the hypothalamus from detecting “real” estrogen, and the hypothalamus, in turn, causes the pituitary gland to secrete more gonadotropins, such as FSH and LH. FSH and LH stimulate the ovaries, the testes to produce more estrogen in women or testosterone in men.

This property of clomiphene is widely used in the treatment of women with premature loss of ovarian function and for the induction of ovulation. However, long-term use of this drug is not safe, as it increases the risk of ovarian cancer.

Pharmacology

Clomid is recommended for the treatment of women with ovarian dysfunction. Many women who fail to get pregnant have a disrupted ovulation process. Among patients with ovulation problems, there are patients with polycystic ovary syndrome and patients with unknown causes of amenorrhea. Clomid is prescribed only after a complete study of the menstrual cycle and determining the cause of the violation.

In the treatment of clomid, the time of reception is of great importance. To determine ovulation, the blood is examined and the body temperature is checked. If the fact of ovulation is established, start taking clomid. As a rule, clomid is prescribed on the fifth day of the cycle. Usually clomid is taken for 3-6 cycles. Long-term treatment with the drug is not recommended.

Mechanism of action of clomiphene

Clomid is a powerful medication. However, if the correct dosage and short treatment periods are observed, it can help with female infertility. Clomiphene is similar to estrogen. It interacts with estrogen receptors in the hypothalamus and blocks these sites. In this case, the brain receives a signal about the insufficient amount of the hormone estrone in the body. This causes an increase in the level of gonadotropins, which increase ovarian stimulation for the production of estrogens. This leads to the synthesis of the hormone in both the adrenal glands and ovaries. Increasing the level of estrogen is important for the fertilization process.