Ovulation induction

What is ovulation induction?

Ovulation induction is an artificial stimulation of the egg maturation process with the help of medications.

What are the indications for ovulation induction?

Ovulation induction is carried out according to strict indications, since the drugs used for this have many serious side effects in women of certain categories:

  • For the treatment of amenorrhea in some cases
  • To stimulate ovulation in women with anovulatory cycles
  • To regulate the cycle in women with irregular menstrual cycles
  • To obtain several eggs in the ovaries of women preparing for IVF (in vitro fertilization) or intrauterine insemination (superovulation).

Healthy women with regular menstrual cycles are not recommended to carry out ovulation induction.

What methods can determine the presence of ovulation?

There are several methods for determining ovulation. Ovulation tests are becoming more popular due to the ease of implementation. They are based on determining the level of LH in a woman’s urine using special strips. The growth and peak of LH levels is observed 32-36 hours before ovulation. Usually, this test is used 2-3 days before the expected ovulation (in women with a 28-day cycle – from 12 to 15 days). In women with irregular cycles, the test should be used from the 11th to the 20th day of the cycle. Ovulation in such women can be confirmed within 5 days in 85% of cases, and within 10 days in 95% of cases. Sometimes ovulation may be absent, which happens normally, however, if ovulation is absent for 2-3 cycles, you need to consult a doctor.

Another method of determining ovulation is ultrasound. Ovulation usually occurs with a follicle size of 1.8‑2.5 cm. This method is more reliable if several ultrasounds are performed in the middle of the cycle every other day. The same method is used by many doctors to control ovulation in infertility clinics. A less common method is an endometrial biopsy with histological examination, which is performed the day before the expected menstruation. This method also allows you to determine the readiness of the endometrium for possible implantation of the fetal egg. Some doctors suggest measuring the level of LH and estradiol in the blood for several days of the cycle. Less and less often women use basal body temperature measurement, since this is not the most reliable method for determining ovulation.

Other questions about ovulation induction in women

Is it possible to use ovulation induction in women who have borderline ovarian tumors removed?

According to new research, it is considered safe to conduct ovulation induction in women after removal of borderline ovarian tumors.

What are the methods of ovulation induction?

Ovulation induction is carried out by one or a combination of several medications, which include clomiphene citrate, FSH, hCG, MGH (human menopausal gonadotropin), bromocriptine, cabergoline, gonadotropin-releasing hormone and its analogues, LH and a number of others.

What are the indications for clomiphene citrate induction?

There are not so many indications for ovulation induction, although many doctors have been abusing this method recently. Induction is indicated for women with rare menstruation or lack of menstruation, those who cannot find out the cause of infertility, with moderate endometriosis, or according to the requirements of the women themselves. The standard dose is 50 mg, for 5 days at the beginning of the cycle. The level of ovulation, pregnancy and the outcome of pregnancy are the same if induction is started on the 2nd, 3rd, 4th or 5th day of the cycle. The doctor should monitor the effectiveness of induction. This can be done by ultrasound, measurement of basal body temperature, determination of the level of estrogen in the blood.

about ovulation induction

When does ovulation occur after the use of clomiphene citrate?

Ovulation occurs most often 5 days after the last dose of clomiphene citrate is administered, however, in many women ovulation can occur from 10 to 23 days of the cycle, so in such cases it is important to monitor the development of follicles using ultrasound.

What are the side effects of using clomiphene citrate that can hinder pregnancy?

Since clomid is an antiestrogenic drug, it can cause inferiority of cervical mucus, which is very important in the fertilization process, and create a barrier to sperm. Even with successful ovulation, such women may have difficulty conceiving due to the artificial cervical factor of infertility created by doctors. Therefore, to control the quality of cervical mucus, experts recommend conducting a postcoital test in the first half of the cycle after each induction with clomiphene citrate. Another negative result of using clomiphene is a decrease in the quality of the endometrium: it becomes thin and of poor quality for successful implantation of the fetal egg. Some side effects are associated with the occurrence of hot flushes (10% of cases), visual impairment, vaginal dryness, hyperstimulated ovarian syndrome. In 10% of cases, there is a double pregnancy (twins). Some women may experience the growth of ovarian cysts, so before conducting a course of ovulation induction, it is necessary to conduct an ultrasound of the ovaries. Insufficiency of the luteal phase is also not a rare side effect when using clomid (observed in 50% of cases).

When is ovulation induction with clomiphene citrate contraindicated?

Induction of ovulation with this drug is contraindicated in the presence of ovarian cysts, pregnancy, liver diseases.

To be continued

What vitamins are needed to get pregnant quickly?

Get pregnant quickly? In this article, questions will be considered about whether it is possible to bring the onset of pregnancy closer with the help of additional means.

How to get pregnant quickly?

Before an important life stage – bearing and giving birth to a child – a woman must undergo a medical examination. It includes examination and delivery of tests. Experts advise to do the same to a man. This is necessary in order to eliminate the risk of infectious diseases, possible future pathologies of the fetus, to receive treatment. The expectant mother should be sure that nothing threatens her health, be observed by specialists in case of chronic diseases.

Wondering what to do to get pregnant quickly, a man and a woman should not only be examined by specialists. Nutrition and lifestyle also have an impact on the reproductive activity of the body. So, for the sake of the health of the unborn baby and a calm pregnancy, it is worth giving up bad habits, expanding the diet, including all the necessary vitamins and minerals, resting more, trying to avoid stressful situations and emotional stress. If the future mother and father follow these recommendations, then the chances of an early pregnancy increase significantly.

What vitamins should I take?

Essential vitamins for women’s and men’s health can be obtained from natural food. So, it is necessary to include in the diet dishes from meat, cereals, vegetables, fruits, fresh dairy products – they are a source of carbohydrates, fats, proteins and micronutrients. The food should be full and varied. You should avoid snacking on the go, eating fast food. It is also necessary to adjust the water balance in the body. In order to get the right amount of liquid, you should drink at least two liters of water a day.

get pregnant quickly

What vitamins should I take to get pregnant quickly? The composition of such combined preparations includes, at least, folic acid, vitamins D and E. Experts advise taking them once a day, except folic acid – these vitamins should be drunk one tablet 3 times a day.

The body is enriched with useful substances, the hormonal balance returns to normal, the nervous system of the unborn child is protected from various disorders. In addition, if a woman takes care of herself and adheres to proper eating habits, she feels a surge of strength, her condition improves, which also contributes to a faster onset of pregnancy and the ability to safely carry a child.

Pills for pregnancy

What pills to take to get pregnant quickly? Are there drugs that enhance sexual function? Yes, however, you should not try to purchase and take them yourself, without the permission of a doctor. Only after the specialist examines the results of the tests from the woman, he can prescribe treatment. Otherwise, a woman risks seriously harming her health and even provoking infertility.

Everyone knows that the onset of the ovulation period promotes conception. Therefore, doctors prescribe drugs that stimulate this process and bring the onset of pregnancy closer.

Stimulation of pregnancy with the help of medications is a very difficult issue. Only a doctor can prescribe effective infertility treatment or help bring the onset of pregnancy closer, and it should be remembered that drugs (for example clomid (clomiphene)) that stimulate reproductive activity can have unpleasant side effects.