Women suffer from menstrual cycle disorders and infertility

The menstrual cycle is one of the most mysterious phenomena in human biology. Why did our species develop a rhythmic ovulation that is independent of coitus? What is the biological meaning of menstrual bleeding, which is absent in other mammals? There are also more practical questions: it is known that physical and psychological stress, as well as body weight, significantly affect the menstrual cycle – but how and why does this happen? In search of answers, we turn to high-level processes – the analytical system of the hypothalamus.

The extension of the genus requires an optimal external and internal environment. A woman should be safe, have a favorable social environment, and have unrestricted access to nutrients. Otherwise, the pregnancy may be terminated or the fetus will suffer from developmental defects.

How can the body assess the many external and internal factors and make a choice: to take the risk of conception now-or to sacrifice part of the fertile time, waiting for more suitable conditions? Taking into account the complexity of the task, we can say that the choice of physiological states suitable for conception cannot be carried out by the pelvic organs. This function should be performed by an organ that “knows” the whole physiological context.

Menstrual cycle: Stress and procreation

In modern biology, the concept of “stress” means an overload of the adaptive abilities of the body. As a universal response to long-term adverse conditions, the hypothalamus increases plasma cortisol (and CSF) through the pituitary-adrenal system. In response, cortisol, among other things, suppresses the secretion of GnRH. This occurs in a variety of chronic conditions, different in nature and origin, but uniformly interpreted by the hypothalamus as stress: depression and anxiety disorders, diabetes, alcoholism, violation of the “sleep – wake” mode (working night shifts). Excess cortisol is also seen in many professional athletes.

menstrual cycle

So, the species Homo sapiens is adapted to long-distance running, in which endogenous cannabinoids enter the blood. At the dawn of human history, they made it easier to run for hours during times of migration and hunting, providing an analgesic and euphoric effect. Of course, they also inhibit the release of GnRH, since such severe trials are not combined with the prolongation of the genus. This probably explains some of the cases of amenorrhea among the runners these days.

Social and psychological stress

Human society has undergone significant changes over the last millennium. However, social distress, lifestyle changes, and information overload involve the same stressful mechanisms as the threat to physical survival.

In many mammals, females fight among themselves for resources and those partners that could provide tactical and genetic advantages to future offspring. In primates, a subordinate social position causes an increase in cortisol plasma. At the same time, the peak luteinizing hormone emissions required for ovulation are reduced. As resources decrease and aggressiveness increases within the community, conception is most promising in the dominant female. Aggression, including between close relatives, seems to play an important role in the suppression of ovulation among subordinate individuals.

Menstrual cycle and microecology of nutrition

In addition to the three main nutritional classes: proteins, fats and carbohydrates – with each meal, the human body receives microscopic doses of regulatory substances that have not nutritional, but informational value. The availability of vitamins of plant and animal origin historically included Homo sapiens in specific food chains, and the microelement composition of the environment determined favorable zones for habitation. Thus, vitamins and trace elements, whose importance is often underestimated, combine the biogeocenosis with individual physiology. The female body, constantly looking for optimal conditions for the prolongation of the genus, can not ignore such data.

Today, humanity has spread across the globe everywhere, often spending most of their lives moving. Thus, medical science is faced with the task of compensating for the change of ecological subsystems, which in market conditions is available only through the development of universal adaptive complexes. The degree of their influence is individual, because each organism is unique. However, such substitution drugs occupy their own therapeutic niche along with higher-level treatment methods.

Conclusion

It is possible that both in cases of metabolic stress and in cases of chronic psychological threats, the hypothalamus acts uniformly: it seeks to protect the body by reducing energy consumption and preventing risky pregnancy. This should be taken into account in patients with functional amenorrhea. In such cases, replacement therapy alone may not be sufficient, as it does not affect adrenal hyperfunction, body weight, and psychological problems. Even with artificially induced ovulation, subsequent pregnancy is threatened by ongoing psychological and / or metabolic stress. In other words, the full restoration of sexual function requires the correction of a fundamental problem-lifestyle.

High cholesterol affects the conception of a child

It will be difficult for a couple to conceive a child if both the man and the woman have high cholesterol levels.

This conclusion was made by scientists from the National Institute of Child Health and Human Development (Rockville, Maryland).

The researchers found that couples with cholesterol levels had difficulty conceiving, as opposed to couples whose cholesterol levels were normal. In the course of the study, experts processed data from 501 married couples from Michigan and Texas. All couples tried to conceive and were not treated for infertility.

After evaluating the levels, phospholipids, triglycerides, and total lipids in each study participant, the researchers concluded that cholesterol was the greatest factor in infertility.

Blood pressure affects the ability to procreate, as it is a kind of building material for male and female hormones. Estrogen and progesterone in women, testosterone in men-these hormones play an important role in a couple’s ability to conceive a healthy child. They are also important for the processes of seminal fluid formation, ovulation, fertilization, and maintaining a healthy pregnancy process.

Do not forget, if you are all right with cholesterol, then clomid can increase the success of conception. The main thing is to consult your doctor.

How to lower bad cholesterol

Just one serving of legumes a day can lower the level of bad cholesterol, scientists have found.

The results of the latest study were published in the journal CMAJ.

It is known that cholesterol is necessary for our body – it is involved in the synthesis of sex hormones, vitamin D and other biological compounds, in contrast to bad cholesterol, or low-density lipoprotein, which is recognized as one of the most important risk factors for the development of cardiovascular diseases. Low-density lipoproteins are poorly soluble, cholesterin from them often precipitates and is deposited in the vessels in the form of atherosclerotic plaques.

high cholesterol

As part of a joint study of scientists from Canada and the United States, 26 studies were analyzed aimed at studying the effect of eating legumes on lowering cholesterol levels. The study involved 1,037 people.

“We believe this is due to the fact that men often pay less attention to their daily diet and have higher cholesterol levels,” says Dr. John Siwenpaper of St. Michael’s Hospital in Toronto, lead author of the study. “To prevent many chronic diseases, normalize body weight, blood pressure, blood glucose levels, and reduce the amount of cholesterol in the body, it is simply necessary to regularly consume crops such as Turkish peas, lentils, and beans.”

However, it should be noted that, despite the decrease, some side effects were recorded, in particular, increased flatulence, bloating, diarrhea, or even constipation.

Absence of pregnancy

Absence of pregnancy – one of the causes of female infertility is premature ovarian failure. In 74% of cases, the only chance to get pregnant is to perform in vitro fertilization using donor oocytes. In this regard, it is relevant to search for new approaches to solving this problem.

The incidence of premature ovarian failure in the female population is 1.5%, and in the structure of secondary amenorrhea-up to 10%. There are several theories that explain the causes of ovarian insufficiency: pre-and post-pubertal destruction of oocytes, chromosomal abnormalities, autoimmune disorders, etc. A typical portrait of a patient: a young girl with the presence of menopausal symptoms, who does not become pregnant against the background of secondary amenorrhea. The diagnostic criteria for insufficiency include oligomenorrhea, amenorrhea for 4-6 months, the level of follicle-stimulating hormone (FSH) in the blood above 25 IU/l in two studies with an interval of at least four weeks, a decrease in the level of estradiol (E2) and anti-muller hormone (AMH) in the blood.

Hormone replacement therapy is recognized as a pathogenetic approach to treatment. However, at the moment, there are no effective treatment regimens that can improve the prognosis for fertility recovery. An alternative method of treatment is placental therapy with the drug Melsmon.

Clinical case absence of pregnancy

A 22-year-old patient came to the medical center with complaints about the absence of menstruation (amenorrhea) for a year and the absence of pregnancy for four years, a feeling of hot flashes up to ten times a day, hyperhidrosis, decreased libido, lethargy, increased fatigue, shortness of breath, insomnia. The patient has been married for four years, the first marriage, with a regular sexual life in the absence of any methods of contraception, pregnancy in this marriage did not occur. The patient’s husband underwent a study of the state of reproductive health. The male factor of infertility is excluded. Menstruation in a patient from 11 years old, established immediately, duration-five days, after 30 days.

absence of pregnancy

From the anamnesis, it is known about the violation of the menstrual cycle in the form of scanty bloody discharge (oligomenorrhea) and their gradual disappearance. When examined in the mirrors, a fibrous polyp of the cervical canal was found. A hysteroscopy was performed with separate diagnostic curettage and removal of the cervical canal polyp. Histological conclusion: glandular endometrial hyperplasia with elements of polyposis on the background of chronic endometritis. Fibrotic polyp of the cervix. The somatic history is not burdened. No previous tests have been performed for sexually transmitted infections. He has no professional harms or bad habits. For four months, in order to regulate the menstrual cycle, she took Regulon (she did not take the drug clomid), then stopped taking it due to a sharp increase in the body mass index (after the withdrawal of the drug Regulon, the weight returned to its previous values).

When collecting a family history, it turned out that the mother’s menstrual function stopped at the age of 34. Due to the lack of pregnancy, the family is under stress.

Difficulties with conception and clomid

Approximately 20% of married couples who have difficulties with conception, this is because, a woman’s ovaries do not produce and release an egg in each menstrual cycle (anovulation). Clomid acts by causing a gland in the brain (the anterior pituitary gland) to release hormones that stimulate ovulation.

It must be remembered that there are many causes of anovulation, so Clomid may not be effective in all cases.

When accepting Clomid, it should be 28-32 days from the beginning of one period to the next. Your ovaries should release the egg 6-12 days after a course of Clomid. You should have sexual intercourse at this time to increase your chances of conception.

If menstruation does not arrive after the 35th day there are two likely possibilities: the dose of Clomid was not enough to get ovulation, or you are pregnant.

If your menstrual period is overdue, contact your doctor who wrote you a prescription for clomid and he will advise you what steps to take.

difficulties with conception

Before taking Clomid, your doctor should perform a gynecological examination before you start taking the drug. This is necessary in order to ensure that there are no physical conditions that could prevent you from becoming pregnant or that could indicate that Clomid is not the right remedy for you.

Do not take Clomid if you are allergic to any of the ingredients of the drug. Also, do not take Clomid if you are pregnant.

To avoid accidental ingestion in the early stages of pregnancy, you should perform tests during each treatment cycle to determine if ovulation is occurring. You should have a pregnancy test before starting your next course of Clomid therapy.

Tell your doctor immediately if you notice the following side effects:

  • nausea or vomiting;
  • breast discomfort;
  • headache
  • insomnia, nervousness, depression, fatigue, dizziness, or delirium
  • rash or skin irritation;
  • increased frequency of urination;
  • hair loss;
  • fever;
  • vaginal discharge;
  • seizures;
  • vision problems;
  • increased heart rate;
  • heartbeat;

In general, the drug is absolutely safe. We wish you good health and a successful conception of the child, even if you are currently experiencing difficulties with conception!

How to stimulate ovulation?

So, how to stimulate ovulation? Problems of the reproductive system of the female body, as you know, can sometimes be solved without surgical intervention. It is enough just to go to the pharmacy for the “magic” pills prescribed by the doctor the day before. And, while your eyes are scattered when choosing medicines, we will help you understand the principle of the most popular of them, and what is the effect of each.

How to stimulate ovulation: Clomid.

Clomid was originally developed as a pilot version of a universal drug for breast cancer, but, failing to meet high expectations, began to be used as a drug to stimulate ovulation among women who want to become pregnant. So, clomid can be recommended by doctors in three cases:

  1. If the absence of ovulation is caused by a previously diagnosed polycystic ovary syndrome.
  2. If infertility does not have a certain genesis, that is, with ideal medical indicators, a woman still does not get pregnant after more than a year of intensive attempts. In this case, clomid is usually used in conjunction with another drug – metformin, which, in turn, increases the level of insulin and promotes ovulation.
  3. If in vitro fertilization (IVF, ICSI, etc. ) requires additional guarantees of the success of the procedure. Although from a medical point of view, this use of clomid is not sufficiently justified, many patients personally ask their doctor to include clomid in their treatment course, since this drug is considered effective when it comes to increasing the chances of becoming pregnant.

Studies and many years of experience show that about 80% of women who have problems with ovulation, observe the release of an egg from the ovaries after the first application of clomid. However, only 30% of patients manage to get pregnant immediately after the first cycle. However, a six-month course of clomid use is considered quite optimal, so even if you did not manage to get pregnant after your first use, you still have a good chance of seeing the long-awaited two stripes over the next few months, provided that you follow the medication course.

how to stimulate ovulation

The chronology of the process of using clomid is very simple. After your doctor has conducted a full medical examination and written out a prescription for the purchase of the drug, you can safely go to the pharmacy. Before use, it is necessary to consult a doctor about the interval of use, but, as a rule, clomid tablets are taken on the third to seventh day of the menstrual cycle. After a week from the beginning of the menstrual cycle, lead an active sexual life, preferably with a break interval of one day, so that your partner has time to accumulate sperm ready for fertilization. If by the tenth day of your menstrual cycle, your cervical mucus has the consistency of egg white, it means that you are on the right track, and that ovulation will occur soon. After another week or two, you can start using pregnancy tests and hope for the best.

The side effects of clomid are insignificant, and do not pose a direct threat to the female body. In the most frequent cases, abdominal pain, insomnia and weight gain are observed. The worst possible development is the appearance of ovarian cysts or the diagnosis of ovarian cancer. However, the chance of such consequences appearing is very, very small.

Menstrual cycles and ovulation

The duration of the female cycle varies. The most common cycle duration is between 23 and 35 days. The difference in the length of the menstrual cycles, as a rule, concerns the period before ovulation (the so-called follicular or follicular phase). In most women, from ovulation (when the egg comes out of the ovary) to the beginning of menstruation, it takes from 12 to 16 days (the so-called luteal phase).

Phases of the menstrual cycles

Menstruation: The first day of the menstrual cycles is the first day of menstruation (day 1). Menstruation then lasts from 3 to 7 days. Surely, you know that in the presence of menstrual pain, the most severe pain you experience in the first few days of menstruation. This is because your hormones actively promote the rejection of the uterine mucosa that has grown during the previous menstrual cycle.

Preparing for ovulation: At the beginning of your cycle, the pituitary gland, located at the base of the brain, produces follicle-stimulating hormone (FSH). This is the main hormone that stimulates the ovaries to produce eggs. Follicles are fluid-filled vesicles in the ovaries. Each follicle contains an immature egg. FSH promotes the maturation of a certain number of follicles and the production of the hormone estrogen. On the first day of menstruation, the estrogen content is at its lowest level. Then it begins to rise along with the maturation of the follicles.

As the follicles develop, usually one of them becomes “dominant”, and in this large follicle the egg matures. At the same time, the growing level of estrogen in the body is responsible for saturating the lining of the uterine cavity with nutrients and blood. This is so that in the event of pregnancy, the fertilized egg will have all the nutrients and support needed for growth. High levels of estrogen also contribute to the formation of mucus, a “sperm-friendly” environment (or scientifically, cervical (cervical) mucus of the fertile phase). Perhaps you have paid attention to not thick sticky discharge, which may have a cloudy whitish hue. Spermatozoa move more easily through this mucus and survive for several days.

Understanding the ovulation cycle

Ovulation: The level of estrogen in the body is steadily increasing, and at some point it leads to a sharp increase in the level of luteinizing hormone (ovulatory surge of LH). The surge of LH leads to the rupture of the dominant follicle and the release of a mature egg from it, which then enters the fallopian tube. This process is called ovulation.

Menstrual cycles and ovulation

Many women believe that ovulation occurs on day 14, but 14 days is the average, and most women usually ovulate on another day of the menstrual cycle. The day of ovulation differs from cycle to cycle. Some women claim to experience a pain spasm during ovulation, but most women do not feel anything, and ovulation passes without any signs.

After ovulation: After release, the egg moves along the fallopian tube towards the uterus. Its life cycle is up to 24 hours. The life cycle of the sperm is more variable, however, and is usually between 3 and 5 days. Thus, the days immediately preceding ovulation and the day of ovulation itself are the most fertile – it is then that you have the greatest chance of becoming pregnant. Immediately after ovulation, the follicle begins to produce another hormone – progesterone.

Progesterone contributes to the subsequent preparation of the uterine mucosa for the reception of a fertilized egg. Meanwhile, the empty follicle in the ovary begins to shrink, but it continues to produce progesterone and begins to produce estrogen. During this time, you may experience premenstrual tension syndrome (PMS), such as breast soreness, bloating, drowsiness, depression, and irritability.

IVF pills (IVF preparations)

When using assisted reproductive technologies (ART), as a rule, hormonal drugs (IVF pills) are used. IVF preparations are chemical compounds obtained synthetically, which have the same effect on the body as their own sex hormones.

The drugs are used at the stage of ovulation stimulation, to prepare the endometrium for embryo transfer, as well as to support the luteal phase in early pregnancy.

Below we will look at these medications, but the information on them is in no way a prescription and can not be used by patients on their own without the appointment of the attending physician. Our article is for informational purposes only.

Preparations for ovulation stimulation

Antiestrogens

Clomid (clomiphene, clomiphene citrate, clostylbegite). It is available in tablets of 50 mg. In small doses, it increases the secretion of gonadotropins (prolactin, FSH and LH), stimulates ovulation; in high doses, it inhibits the secretion of gonadotropins. It is used both to stimulate ovulation under the control of ultrasound, and in IVF protocols.

IVF pills

Human Menopausal Gonadotropins

IVF pills: Menopur containing 75ED FSH and 75ED LH (Ferring, Germany). Currently, there is a Menopur-Multidose containing 1200 units of FSH and 1200 UNITS of LC, with the ability to dose the drug using a convenient handle.

Menogon containing 75ED FSH and 75ED LH (Ferring, Germany).

Alterpur-urofollitropin (FSH) , available in doses of 75 and 150 IU; (Ibsa, Switzerland). e

Merional (Ibsa, Switzerland), The ratio of the biological activity of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) is 1:1. It is available in a dose of 75ME and 150ME (the dose is measured by FSH).

Bravel (Ferring, Germany) – urofollitropin (a highly purified follicle-stimulating hormone), is available in a dose of 75 MG FSH.

Previously existing menotropins-Pergonal, Metropin, Humegon – are not currently produced.

The use of estrogens in ART

Estrogens in transdermal (through the skin) or oral (through the mouth) forms are used:

  • in programs using cryopreserved embryos
  • in protocols of superovulation stimulation
  • in patients with endometrial hyperplasia in surrogacy programs.

IVF pills: Proginova 2 mg (Delfarm, France) – dragee for oral administration.

Estrofem 2 mg (NOVO NORDISK, Denmark) – tablets for oral administration.

Divigel 0.5 and 1.0 (Orion Corporation, Finland) – gel for external use in single-dose packages.

Estrogel 2.5 mg (Besins, Belgium) – gel for external use, contains 1.5 mg of estradiol in tubes of 80 g with a measuring spatula.

The Council of Experts of the RARCH (Russian Association of Human Reproduction) recommends continuing estrogen therapy during the first trimester of pregnancy in the absence of their own yellow body, its functional insufficiency or endometrial hypoplasia.

When making a list of drugs that we use in our work, you can not choose the best one or make a universal scheme of stimulation. Depending on the clinical situation, the doctor individually selects the drug and its required dose.

! Attention ! All information on the drugs presented in this article is not intended as a prescription and cannot be used by patients independently without the appointment of the attending physician. The article is for informational purposes only.

How clomid affects the body?

How clomid affects the body: Clomid is a drug in tablet form, which contains clomiphene citrate. This drug is a selective estrogen receptor modulator. This term means that the antiestrogen, by binding to estrogen receptors in a certain area of the body, blocks the effect of female sex hormones, but in other tissues it can act as a natural estrogen. In the sports field, this drug is especially popular in post-course therapy due to its properties to prevent the negative effects of estrogens on the hypothalamus and activate increased testosterone production.

Clomid directly affects the estrogen receptors in the pituitary gland and sex glands. By binding to these receptors in the pituitary gland, the antiestrogen interferes with the process of negative feedback – as a rule, estrogens during the action on the pituitary gland reduce the production of lutenizing and follicle-stimulating hormones, but when using clomid, this process is not carried out in the body. From this, you can perfectly understand how clomid affects testosterone, since these gonadotropins contribute to an increase in the concentration of the main male sex hormone in the body.

How clomid affects the body

It is also worth noting that clomid does not affect the level of estrogens in the blood, it only blocks the work of receptors, but female sex hormones become simply inactive in the body.

What effect does the antiestrogen have on the athlete’s body?

Clomid does not affect the metabolic processes of estrogens in the body, so in the case of using this drug, estrogen is freely destroyed by liver enzymes, and does not accumulate in the athlete’s body. To fully understand the principle of the effect of clomid in the body, it is necessary to consider in detail how the antiestrogen affects a particular process. Next, let’s look at the most popular questions:

  • How does clomid affect the spermogram? Initially, since the 70s of the last century, clomid was used as a drug for the treatment of infertility – both male and female. For men, this drug allowed them to fight idiopathic oligospermia – the missing number of sperm cells that are necessary for fertilization of the egg. Therefore, after taking antiestrogens, an increase in the number of active spermatozoa may be observed in the spermogram.
  • How does clomid affect potency? Antiestrogen in sports practice contributes to the normalization of the functioning of the hypothalamus-pituitary-testicular arch. As a result, the concentration of natural testosterone in the body of a man increases, which has a positive effect on erectile function. Most athletes after a course of the steroid are in the so-called “hormonal pit”, which can negatively affect the sexual life. As a result, with the use of clomid, the athlete can observe an improvement in the quality of sexual life, it should also be noted that the timely start of post-course therapy with clomid will avoid testicular atrophy.

To suppress aromatization in the body, aromatase inhibitors – anastrozole, letrozole, or in extreme cases, proviron-are best suited. These drugs, especially the first two, perfectly cope with the symptoms of gynecomastia, excessive fluid retention, high blood pressure and other signs of aromatization.

Clomid, in turn, is used during post-course therapy, while aromatase inhibitors are taken mainly on the course of anabolic and androgenic substances. It allows you to normalize the production of natural testosterone in the body in a short time, and it also eliminates the symptoms of gynecomastia that appeared after a course of steroids. The optimal dosage of antiestrogen is calculated based on how heavy the course was – how many steroids were present on the course, how large the dosages were.

What negative reactions should you be prepared for on the clomid course?

It is not enough to find out how clomid affects libido and spermogram. Also, before taking any medication, it is necessary to find out what side effects an antiestrogen can cause. Failure to comply with the recommended dosages, the optimal duration of the course may lead to the following negative reactions:

  • vertigo;
  • feeling sleepy or, conversely, sleep problems in the form of insomnia;
  • disorders of the digestive system in the form of nausea or vomiting;
  • frequent headaches;
  • the drug is also able to have a toxic effect on the liver, but if you compare it with another fairly popular antiestrogen tamoxifen, its toxicity is much less;
  • it is worth noting how clomid affects vision, neglect of the rules of taking the drug can lead to serious violations of visual function.

The above-mentioned undesirable effects occur in quite rare cases, and if they are observed, they quickly pass after stopping the use of antiestrogen. It is also worth adding that the use of clomid increases the risk of blood clots. But to minimize this effect during the post-course therapy with the use of antiestrogen, it is necessary to increase the volume of consumption of purified water – by at least one liter per day.

How long it will take to recover is calculated individually, depending on the severity of the course. As the reviews indicate, clomid is a fairly effective antiestrogen. Representatives of sports disciplines speak about it mostly positively, negative reviews describing the side effects of clomiphene citrate can be found quite rarely. Many athletes note that with its help it is possible to recover perfectly in a short period of time after a course of anabolic and androgenic steroids, and to minimize losses after AAS.

The main mistakes when trying to get pregnant

Most likely, you have at least one friend who, after getting pregnant, said: “It happened at the exact moment when I stopped thinking about it.” It’s annoying, frustrating, and nerve-wracking, especially when all you want is to have a baby. What prevents you from getting pregnant?

It seems that nothing will work-but your friend is telling the truth. Stress can be one of the main reasons why you can’t get pregnant: high levels of the stress hormone cortisol can negatively affect fertility.

A study of American scientists who followed 400 couples trying to get pregnant found that women with high levels of alpha-amylase (a stress indicator) were 29% less likely to get pregnant than women with a normal indicator.

Experts say that constant stress reduces the production of hormones responsible for a stable cycle.

Relax and try to let go of the situation for a while. Learn to meditate, sign up for yoga.

Mistake #2: Doing too much/not enough

If you’re going to do it – do it right! Many couples believe that if you” save ” sperm and do not have sex for a week, the chances of conception will increase significantly. This is not true. After about a week of abstinence, sperm motility decreases markedly.

For successful conception, doctors recommend having sex every day or every other day for a week before and including the day of ovulation. More frequent sex can negatively affect the ability of sperm to fertilize, and if you do it less often – you can skip the window of conception.

So, if your sex life has long been not as stormy as at the beginning of the relationship, this is a good reason to diversify it.

trying to get pregnant

It would seem that the 21st century is in the yard, but many women still continue to believe in the miraculous power of douching. It seems that everything is logical: with any infection, improper nutrition, the presence of bad habits, the environment in the vagina becomes acidic.

Sperm in such an environment dies and cannot fertilize the egg, so many people use a weak solution of soda to make the environment alkaline and create favorable conditions for conception. But doctors are opposed to this method: soda kills not only harmful microorganisms, but also useful ones, thus violating the natural pH of the vagina.

In addition, douching with soda can exacerbate inflammatory processes and diseases such as erosion and damage to the cervix, which a woman often does not know about without visiting a gynecologist.

If the attempt to get pregnant fails, remember that you can use, for example, clomid, taking it, you increase your chances of pregnancy.

Trying to get pregnant: Don’t blame yourself

Speaking about infertility, we usually believe that the problem is on the part of the woman. But in reality, the responsibility lies equally with both partners.

Doctors say that in 40% of cases of infertility, the cause should be sought from the man, and in another 40% – from the woman. The remaining 20% is compatibility, a combination of both partners. But don’t panic too soon.

Remember that a healthy couple needs from 6 months to a year to successfully conceive.

The most common mistake is the wrong definition of the day of ovulation. In most women, it occurs in the middle of the cycle, but this applies to women with a 28-32-day cycle. Ovulation usually occurs 14 days before the start of menstruation. Therefore, if you have a 24-day cycle, then ovulation will occur on day 10.

If your cycle is noticeably longer, say 42 days, then it can be assumed that you ovulate less frequently, not in every cycle. In this case, as well as if you have an irregular cycle (in this case, ovulation can be both on day 6 and on day 21), or you do not remember when you last had your period, forget these rules.

Another mistake when trying to get pregnant

A lot has already been said on this topic, but it will not be superfluous to repeat it: it is necessary to give up bad habits at least a year before trying to get pregnant.

Why do women continue to drink alcohol and smoke, knowing how harmful this affects the ability to conceive? Doctors around the world warn: the first trimester is the most important in the formation of the child’s body. There is no amount of alcohol that is safe for him.

But some expectant mothers, drinking alcohol in the early stages, do not yet know that they are pregnant. Therefore, if you do not protect yourself, in relation to alcohol and cigarettes, act as if you are already pregnant-simply, do not use it or at least reduce it to a minimum.

Clomid ovulation

The main purpose of Clomid is to induce ovulation in women who do not ovulate or do not ovulate regularly. Between 70 and 80 percent of women taking Clomid will ovulate during the first cycle of treatment. Of course, ovulation is only the first step. Your chance of getting pregnant within a few cycles is approximately 35 percent. If you haven’t gotten pregnant in six months, it’s time to switch to another treatment.

What are the chances that Clomid will work in the first month?

Depending on which studies you refer to, the probability of conception within a single cycle of Clomid treatment is between 7 and 30 percent. The effectiveness of Clomid varies depending on the cause of infertility.

Keep in mind that those who do not have fertility problems are about 25 percent more likely to get pregnant in any given month. If you don’t get pregnant in a month, don’t panic. The need for more than one cycle is common.

What are the chances of getting pregnant after many cycles on clomid?

A literature review published in the journal Human Reproduction reviewed several studies on clomid. In total, Clomid success rates for more than 5,000 women were included. In this study, they found that:

  • 73 percent eventually ovulated on clomid
  • 36 percent eventually reached pregnancy
  • 29 percent gave birth

The birth rate is lower than the pregnancy rate due to miscarriages. Clomid does not seem to increase the risk of miscarriage.

clomid ovulation

Other studies have reported that when using Clomid, the percentage of successful pregnancies is between 30 and 40 percent. Again, the birth rate will be lower due to pregnancy loss.

However, the success of Clomid (clomid ovulation) also depends on why you can’t get pregnant. Clomiphene citrate may work well for people with ovulation problems. But what if ovulation isn’t a problem?

Another study, conducted in Scotland, looked at success rates for couples who were found to have infertility. The couples were randomly assigned to one of three groups: “wait-and-see”, clomid-only treatment, or clomid with IUI. The most effective treatment group was the IUI plus Clomid group, which achieved a 22 percent fertility rate. The clomid – only treatment group did the same with couples who received no treatment at all.

Does the day you start treatment with clomid matter?

Clomid is taken for five days. Treatment can be started as early as the 2nd day of the menstrual cycle or as early as the 5th day. However, most doctors either prescribe clomid on days 3, 4, 5, 6, and 7, or take it from you on days 5, 6, 7, 8, and 9.

Does it matter which protocol your doctor chooses? Yes and no. In order to cause ovulation, treatment is carried out from day 5 to day 9. If your doctor wants to” improve ” ovulation, you will probably take Clomid on days 3 to 7.

However, when it comes to pregnancy and ovulation success rates, studies have found no advantages or disadvantages.

Your chances of getting pregnant are the same, regardless of which protocol your doctor prefers to start taking Clomid.

Remember that while you may be mostly familiar with clomid treatment and possibly IVF, there are actually many more infertility treatment options that you should consider. Always talk to your doctor if you’re concerned about the next step or if Clomid isn’t working as well as you hoped.