Clostilbegyt (clomiphene) and pregnancy – what you need to know

Clomiphene citrate (Clostilbegit, Clomid, and other trade names) is a fertility drug that has been used since the 1950s. Dr. mark P. Leondires of the Association of reproductive medicine of Connecticut claims that the drug was originally used for the treatment of breast cancer because it has anti-estrogenic properties. However, clomiphene has also been found to help induce ovulation, and there is a long and close association between it and pregnancy. As a result, it has since been used as a drug to stimulate natural ovulation in women who want to get pregnant.

In what cases can clomiphene help you get pregnant?

When it comes to clostylbegitis and pregnancy, who can take the drug and under what conditions?

Polycystic ovary syndrome

Doctors usually recommend clostilbegyt for the treatment of disorders of ovulation due to polycystic ovary syndrome (PCOS).

Infertility in violation of the menstrual cycle or ovulation

In addition, it can also be used to stimulate ovulation in women with unexplained infertility – in the event that, despite the normal physical condition and good laboratory results, it is not possible to conceive a child. Clomiphene is also sometimes used in combination with metformin (Glucophage, Siophor, and other trade names), a drug commonly used to regulate insulin levels, which can further promote ovulation.

In the case of assisted reproductive technologies

Clomiphene can also be used before applying various reproductive technologies to achieve pregnancy, including artificial insemination techniques to increase the chances of pregnancy.

What is the percentage of successful pregnancies when using clomid?

Although this drug is medically approved, and there is a long-known and close relationship between clomiphene and the onset of pregnancy, there is no conclusive evidence of its effectiveness for every woman. If you are trying to get pregnant, you will probably want to know if taking clostylbegit will help you to stimulate ovulation and conceive a child.

Some studies show that treatment with clomiphene in women with ovulation problems can lead to the fact that in most of them (about 80%) the egg is released from the ovaries during the first cycle of taking the drug.

However, ovulation does not mean pregnancy. The chances of getting pregnant during the first cycle are only 30%. And yet, this is almost the same as the usual chances of conceiving a child (25%) in couples who do not have fertility problems. Almost half of the couples treated with klostilbegit, it is possible to conceive during the first six months.

Therefore, you should not be disappointed if you do not get pregnant in the first month of treatment. Treatment with clomiphene is usually limited to 6 consecutive months.

How to get pregnant quickly on clomiphene?

There is some connection between taking clomiphene and pregnancy, as this drug may be effective for some women who want to conceive a child. But the question arises, how quickly to take advantage of this?

  • Get the recipe – It is necessary to obtain a doctor’s prescription for the purchase of Clostylbegite or another analog. However, before the doctor writes a prescription, he will first evaluate how appropriate it is. Women who have been trying to get pregnant for less than a year may be advised to wait until treatment begins.
  • You can save money by buying more affordable analogues – Such medications are not covered by insurance, and it may take several procedures before the attempt to conceive a child is successful. Instead of buying the brand Clomid or Clostylbegit, you can save money and request a prescription for more affordable analogues.
  • Take the drug as prescribed – Tablets clostilbegyt or clomiphene is usually taken from the third to the seventh day of the menstrual cycle. However, some doctors may advise taking them on the fifth or ninth day of the cycle. It is important to remember that the 1st day of the cycle is the day when true menstrual bleeding (menstruation) begins, and not daub (light spotting).
  • No need for a daily ultrasound – Your doctor may suggest you to follow the effect of receiving clomiphene for ovulation, every day of the ultrasound examination. This procedure does not guarantee that pregnancy will occur. So, this is just an expensive way to monitor, and you can opt out of it to save money.
  • Sex every other day – Starting from the seventh day of the cycle, you can plan sexual acts every other day, so that spermatozoa have time to form in the partner’s body. Avoid having more frequent sex, as this can reduce your chances of getting pregnant.
  • Make sure to start ovulating with a test – To check whether ovulation has started, you can use a special test for this. You can buy it without a prescription. He is able to show that it is time for conception. If the ovulation test is positive, sexual intercourse should continue for two consecutive days. After that, you should return to the normal schedule.
  • Check if you are pregnant – On the 28th day or later, with the help of a home pregnancy test, you can check how successful the treatment is. You don’t have to wait too long to find out!

Negative consequences from trying to get pregnant with Clostilbegyt

Although there is a link between taking Clostylbegit and pregnancy, side effects may occur when using it, and they should be given special attention.

Minor side effects

Like all other medications, clostylbegit can cause some side effects. These include abdominal pain and swelling, weakness, nausea, vomiting, insomnia, blurred vision, fatigue, headache, depression, and weight gain. Some women may develop ovarian cysts.

The birth of twins

Women who are treated with fertility drugs have a 10% chance of having twins. This is due to the release of more than one egg per cycle as a result of drug stimulation of ovulation. In rare cases, triple or even larger multiple pregnancies also develop, which can increase the risk of complications such as miscarriage.


Emotional aspects

Infertility treatment can be a source of emotional stress due to waiting and the lengthy treatment process. Therefore, a woman will need the support of a partner or friend to go through all the doctor’s examinations and follow-up steps related to treatment.

Ovarian hyperstimulation syndrome

The use of clomiphene citrate together with other powerful fertility drugs sometimes leads to the development of ovarian hyperstimulation syndrome (OHSS). This condition is characterized by bloating and increased body weight. Some women also experience shortness of breath, pelvic pain, dizziness, nausea, and vomiting. This condition occurs when the ovaries produce multiple eggs. At the same time, they become several times larger than their normal size, releasing fluid into the abdominal cavity. Usually, no treatment is required, although in some cases, hospitalization may be required for monitoring.

Ovarian cancer

While this is a concern, research shows that using fertility drugs does not necessarily increase the risk of ovarian cancer, even if the course takes more than 12 months.

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